Elevated urinary 8-oxo-78-dihydro-2′-deoxyguanosine and serum uric acid are associated with progression and are prognostic factors of colorectal cancer

摘要

Background and purposeOxidative stress is closely related to the pathogenesis of colorectal cancer (CRC). 8-Oxo-7,8-dihydro-2′-deoxyguanosine (8-oxodG) is a typical bio-marker of oxidative stress. Serum uric acid (SUA) is one of the most abundant molecules with antioxidant properties in human blood. This study aimed to explore whether 8-oxodG and SUA could be prognostic factors of CRC.