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Emodin suppresses proliferation migration and invasion in ovarian cancer cells by down regulating ILK in vitro and in vivo

机译：大黄素通过在体内外下调ILK抑制卵巢癌细胞的增殖迁移和侵袭

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ObjectiveAlthough our previous studies have confirmed that 1, 3, 8-trihydroxy-6-methylant hraquinone (emodin) inhibits migration and invasion in epithelial ovarian cancer (EOC) cells, the underlying molecular mechanism remains unknown. Here, the aim was to investigate the effects of emodin on EOC cells and to study further the mechanism underlying this process, both in vitro and in vivo.

机译：目的尽管我们先前的研究已经证实，1，3，8-三羟基-6-甲基蒽醌（大黄素）抑制上皮性卵巢癌（EOC）细胞的迁移和侵袭，但其潜在的分子机制仍然未知。在这里，目的是研究大黄素对EOC细胞的影响，并进一步研究该过程在体内和体外的机制。

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期刊名称 OncoTargets and therapy
作者
Jingjing Lu; Ying Xu; Zhe Zhao; Xiaoning Ke; Xuan Wei; Jia Kang; Xuan Zong; Hongluan Mao; Peishu Liu;
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作者单位

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年(卷),期 2017(10),-1
年度 2017
页码 3579–3589
总页数 11
原文格式 PDF
正文语种
中图分类应用微生物学;肿瘤学;
关键词
emodin ILK epithelial ovarian cancer epithelial–mesenchymal transition Slug xenografts in nude mice;

机译：大黄素;ILK;上皮性卵巢癌;上皮-间质转化;Sl;裸鼠异种移植;

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专利

1. Emodin suppresses proliferation, migration and invasion in ovarian cancer cells by down regulating ILK in vitro and in vivo [J] . Jingjing Lu, Ying Xu, Zhe Zhao, OncoTargets and therapy . 2017,第2期

机译：大黄素通过在体内外下调ILK抑制卵巢癌细胞的增殖，迁移和侵袭
2. NFATc1 regulates cell proliferation, migration, and invasion of ovarian cancer SKOV3 cells in vitro and in vivo [J] . Li Long, Duan Zhaoning, Yu Jihui, Oncology reports . 2016,第2期

机译：NFATc1在体内和体外调节卵巢癌SKOV3细胞的细胞增殖，迁移和侵袭
3. Knockdown of MIR4435-2HG Suppresses the Proliferation, Migration and Invasion of Cervical Cancer Cells via Regulating the miR-128-3p/MSI2 Axis in vitro [J] . Ruijing Wang, Lun Liu, Jinwen Jiao, Cancer Management and Research . 2020,第3期

机译：MiR4435-2Hg的敲低通过调节MIR-128-3P / MSI2轴体外抑制宫颈癌细胞的增殖，迁移和侵袭
4. Inhibitory Effects of Natural Food Dyes Genistein on Invasion of SK0V3 Human Ovarian Carcinoma Cells in vivo and in vitro [C] . Tang Li, Li Yu International Conference on Chemical Engineering and Advanced Materials . 2013

机译：天然食品染料Genistein在体内和体外侵袭SK0v3人卵癌细胞侵袭的抑制作用
5. Neuropeptide Y receptor subtype(s) mediating migration, proliferation, and differentiation of endothelial cells in vitro, and angiogenesis in vivo. [D] . Movafagh, Sharareh. 2004

机译：在体外介导内皮细胞迁移，增殖和分化以及在体内血管生成的神经肽Y受体亚型。
6. Minocycline Suppresses Interleukine-6 Its Receptor System and Signaling Pathways and Impairs Migration Invasion and Adhesion Capacity of Ovarian Cancer Cells: In Vitro and In Vivo Studies [O] . Parvin Ataie-Kachoie, David L. Morris, Mohammad H. Pourgholami -1

机译：Minocycline抑制Interleukine-6其受体系统和信号传导途径并损害卵巢癌细胞的迁移侵袭和粘附能力：体内和体外研究
7. Emodin suppresses proliferation, migration and invasion in ovarian cancer cells by down regulating ILK in vitro and in vivo [O] . Jingjing Lu, Ying Xu, Zhe Zhao, 2017

机译：大蒜抑制卵巢癌细胞的增殖，迁移和侵袭通过在体外和体内进行调节ILK

Emodin suppresses proliferation migration and invasion in ovarian cancer cells by down regulating ILK in vitro and in vivo

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