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Meeting Vitamin D Requirements in White Caucasians at UK Latitudes: Providing a Choice

机译:满足英国纬度白人白种人的维生素D要求:提供选择

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The body gains vitamin D through both oral intake (diet/supplementation) and synthesis in skin upon exposure to ultraviolet radiation (UVR). Sun exposure is the major source for most people even though sun exposure is complex and limited by climate and culture. We aimed to quantify the sun exposure required to meet vitamin D targets year-round and determine whether this can be safely achieved in a simply defined manner in the UK as an alternative to increasing vitamin D oral intake. Data from observation (sun exposure, diet, and vitamin D status) and UVR intervention studies performed with white Caucasian adults were combined with modeled all-weather UVR climatology. Daily vitamin D effective UVR doses (all-weather) were calculated across the UK based on ten-year climatology for pre-defined lunchtime exposure regimes. Calculations then determined the time necessary to spend outdoors for the body to gain sufficient vitamin D levels for year-round needs without being sunburnt under differing exposure scenarios. Results show that, in specified conditions, white Caucasians across the UK need nine minutes of daily sunlight at lunchtime from March to September for 25(OH)D levels to remain ≥25 nmol/L throughout the winter. This assumes forearms and lower legs are exposed June-August, while in the remaining, cooler months only hands and face need be exposed. Exposing only the hands and face throughout the summer does not meet requirements.
机译:人体在暴露于紫外线(UVR)后通过口服(饮食/补充)和皮肤合成获得维生素D。尽管大多数情况下阳光暴露是复杂的,并且受气候和文化的限制,但阳光仍然是大多数人的主要来源。我们旨在量化全年实现维生素D目标所需的日照量,并确定在英国是否可以通过简单定义的方式安全地实现这一目标,以替代增加维生素D口服摄入量的方法。将来自白人(白种人)成年人的观察数据(日照,饮食和维生素D状况)和UVR干预研究的数据与模拟的全天候UVR气候学相结合。在英国范围内,基于十年的气候学,针对预先定义的午餐时间接触方案,计算了每日维生素D的有效UVR剂量(全天候)。然后,计算确定了在户外度过身体所需的时间,以使人体获得足够的维生素D水平来满足全年的需要,而又不会在不同的暴露情况下被晒伤。结果显示,在特定条件下,英国白人在三月至九月的午餐时间每天需要9分钟的日照,以使25(OH)D水平在整个冬季保持≥25nmol / L。假设6月至8月暴露了前臂和小腿,而在其余的凉爽月份中,只需要暴露手和脸。整个夏天仅暴露手和脸不符合要求。

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