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Study of caveolin-1 gene expression in whole adipose tissue and its subfractions and during differentiation of human adipocytes

机译：整个脂肪组织及其亚组分和人脂肪细胞分化过程中Caveolin-1基因表达的研究

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摘要

ContextCaveolins are 21-24 kDa integral membrane proteins that serve as scaffolds to recruit numerous signaling molecules. Specific subclasses of caveolae carry out specific functions in cell metabolism. In particular, triglycerides are synthesized at the site of fatty acid entry in one of these caveolae classes.

机译：洞毒素是21-24 kDa的整合膜蛋白，可作为支架募集大量信号分子。小窝的特定亚类在细胞代谢中执行特定功能。特别地，在这些小窝类别之一中，在脂肪酸进入的部位合成甘油三酸酯。

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期刊名称 Nutrition Metabolism
作者
José M Fernández-Real; Victoria Catalán; José M Moreno-Navarrete; Javier Gómez-Ambrosi; Francisco J Ortega; Jose I Rodriguez-Hermosa; Wifredo Ricart; Gema Frühbeck;
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作者单位

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年(卷),期 2010(7),-1
年度 2010
页码 20
总页数 9
原文格式 PDF
正文语种
中图分类营养学;
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入库时间 2022-08-17 12:27:40

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专利

1. Study of caveolin-1 gene expression in whole adipose tissue and its subfractions and during differentiation of human adipocytes [J] . José M Fernández-Real, Victoria Catalán, José M Moreno-Navarrete, Nutrition Metabolism . 2010,第Supplaa1期

机译：整个脂肪组织及其亚组分和人脂肪细胞分化过程中Caveolin-1基因表达的研究
2. Depot- and obesity-related differences in adipogenesisAdipocyte hypertrophy and hyperplasia are known to facilitate lipid storage in adipose tissues by increasing adipocyte cell size and number, respectively. Adipogenesis is the process resulting in adipose tissue hyperplasia. Although depot-specific differences and obesity-related modulation of adipocyte size are well documented, available data on adipogenesis and adipose tissue hyperplasia are less conclusive. Most studies support a reduction of adipogenesis in the obese state. Preadipocytes of the subcutaneous fat depot appear to be more responsive to adipogenic stimulation compared with those from visceral fat compartments in most studies. A number of studies support the notion that adipose tissue expansion through hyperplasia reduces ectopic lipid excess and obesity-related complications. Several genetic variants have been identified in the genes coding for adipogenesis-regulating proteins. While some of these variants have been clearly associated with the phenotypes of obesity and obesity-related alterations, available data highlight the importance of considering gene–gene and gene–diet interactions. [J] . Julie. Lessard, André. Tchernof Clinical lipidology. . 2012,第5期

机译：脂肪形成与肥胖相关的差异已知脂肪细胞肥大和增生分别通过增加脂肪细胞的大小和数量来促进脂质在脂肪组织中的存储。脂肪形成是导致脂肪组织增生的过程。尽管已经有很多文献记载了贮库特异性差异和肥胖相关的脂肪细胞大小调节，但有关脂肪形成和脂肪组织增生的可用数据尚无定论。大多数研究支持在肥胖状态下减少脂肪形成。在大多数研究中，与来自内脏脂肪区室的脂肪细胞相比，皮下脂肪库的前脂肪细胞似乎对脂肪刺激更为敏感。许多研究支持这样的观点，即通过增生的脂肪组织扩张可以减少异位脂质过多和肥胖相关的并发症。在编码脂肪形成调节蛋白的基因中已经鉴定出几种遗传变异。尽管其中一些变异与肥胖症的表型和与肥胖有关的改变明显相关，但现有数据突出了考虑基因-基因和基因-饮食相互作用的重要性。
3. Genome-wide analysis of gene expression during adipogenesis in human adipose-derived stromal cells reveals novel patterns of gene expression during adipocyte differentiation - ScienceDirect [J] . Melvin Anyasi Ambele, Carla Dessels, Chrisna Durandt, Stem cell research . 2016,第3期

机译：人类脂肪来源的基质细胞在脂肪形成过程中基因表达的全基因组分析揭示了脂肪细胞分化过程中基因表达的新模式-ScienceDirect
4. Connective tissue growth factor (CTGF/CCN2) and Connexin-43 (0x43) expression are upregulated in human adipose-derived stromal cells (hASCs) over the course of osteogenic differentiation [C] . Panetta NJ, Gupta DM, Gupta A, International Society of Craniofacial Surgery International Congress . 2009

机译：在骨质发生分化的过程中，在人脂肪衍生的基质细胞（HASC）中，将结缔组织生长因子（CTGF / CCN2）和Connexin-43（0x43）表达上调
5. Investigating the Use of Human Monocytes and Vascular Smooth Muscle-Like Cells Differentiated from Adipose Derived Stromal Cells for Vascular Tissue Regeneration [D] . Zhang, Xiaoqing. 2019

机译：调查使用从脂肪衍生的基质细胞分化的人单核细胞和血管平滑肌样细胞进行血管组织再生
6. Regulation of CXCR6 Expression on Adipocytes and Osteoblasts Differentiated from Human Adipose Tissue-Derived Mesenchymal Stem Cells [O] . Seung-Cheol Lee, Yoo-Jung Lee, Min Kyoung Shin, 2020

机译：对脂肪细胞和成骨细胞的CXCR6表达的调节分化为人脂肪组织衍生的间充质干细胞
7. Study of caveolin-1 gene expression in whole adipose tissue and its subfractions and during differentiation of human adipocytes [O] . Fernandez-Real, J.M. (José Manuel), Catalan, V. (Victoria), Moreno-Navarrete, J. (José), 2010

机译：整个脂肪组织及其亚组分和人脂肪细胞分化过程中Caveolin-1基因表达的研究

Study of caveolin-1 gene expression in whole adipose tissue and its subfractions and during differentiation of human adipocytes

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