COMPOSITION FOR DIFFERENTIATION INDUCTION OF ADIPOCYTE CONTAINING STEM CELL-DERIVED EXOSOME, REGENERATION OF ADIPOSE TISSUE, AND SKIN WHITENING OR WRINKLE IMPROVEMENT

摘要

#$%^&*AU2017202287B220181108.pdf#####[ABSTRACT] The present invention relates to a pharmaceutical composition for inducing differentiation of adipocytes and/or regeneration of adipose tissues containing, as an active ingredient, an exosome extracted from stem cells differentiating into adipocytes. The exosome shows an excellent expression rate of bioactive factors influencing the differentiation into adipocytes and has the effect of differentiating stem cells into adipocytes. Accordingly, the present invention can be applied as stem cell differentiation inducing agents, injectable preparations for tissue regeneration, fillers for cosmetic purposes, preparations for tissue engineering, etc. Further, the present invention relates to a cosmetic composition for skin whitening, wrinkle improvement and regeneration containing, as an active ingredient, an exosome extracted from stem cells. The exosome contains genes, proteins, growth factors and the like associated with cell proliferation, differentiation and regeneration of stem cells; is a purified component which does not include antibiotics, serums or harmful factors of a culture solution; and is a cell-derived lipid carrier, and thus, the exosome can be applied to functional cosmetic compositions having skin whitening, wrinkle improvement and skin regeneration functions, and preparations for improving scar for cosmetic purposes, etc.