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Increased expression level of corticotropin-releasing hormone in the amygdala and in the hypothalamus in rats exposed to chronic unpredictable mild stress

机译：慢性不可预测的轻度应激大鼠杏仁核和下丘脑中促肾上腺皮质激素释放激素的表达水平增加

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摘要

ObjectiveCorticotropin-releasing hormone (CRH) plays an important role in neuroendocrine, autonomic and behavioral responses to stressors. In the present study, the effect of chronic unpredictable mild stress (CUMS) on CRH neurons was investigated in rat brain.

机译：目的促肾上腺皮质激素释放激素（CRH）在神经内分泌，自主神经和行为应激反应中起重要作用。在本研究中，在大鼠脑中研究了慢性不可预测的轻度应激（CUMS）对CRH神经元的影响。

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期刊名称 Neuroscience Bulletin
作者
Shan-Shan Wang; Xue-Bo Yan; Michel A. Hofman; Dick F. Swaab; Jiang-Ning Zhou;
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作者单位

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年(卷),期 2010(26),4
年度 2010
页码 297–303
总页数 7
原文格式 PDF
正文语种
中图分类神经科学;
关键词
chronic unpredictable mild stress hypothalamo-pituitary-adrenal axis corticotropin-releasing hormone amygdala paraventricular nucleus;

机译：慢性不可预知的轻度压力;下丘脑-垂体-肾上腺轴;促肾上腺皮质激素释放激素;杏仁核;脑室旁核;

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专利

1. Honokiol Exerts Antidepressant Effects in Rats Exposed to Chronic Unpredictable Mild Stress by Regulating Brain Derived Neurotrophic Factor Level and Hypothalamus–Pituitary–Adrenal Axis Activity [J] . Canmao Wang, Danna Gan, Jingang Wu, Neurochemical research . 2018,第8期

机译：通过调节脑衍生的神经营养因子水平和下丘脑 - 垂体 - 肾上腺轴活性，对暴露于慢性不可预测的轻度胁迫的大鼠的大鼠抗抑郁作用
2. Exposure to Chronic Mild Stress Differentially Alters Corticotropin-Releasing Hormone and Arginine Vasopressin mRNA Expression in the Stress-Responsive Neurocircuitry of Male and Female Rats Prenatally Exposed to Alcohol [J] . Lan Ni, Hellemans Kim G. C., Ellis Linda, Alcoholism: Clinical and experimental research . 2015,第12期

机译：慢性轻度应激的暴露差异改变产前暴露于酒精的雄性和雌性大鼠应激反应神经回路中促肾上腺皮质激素释放激素和精氨酸加压素mRNA表达
3. The Antidepressant Agomelatine Improves Memory Deterioration and Upregulates CREB and BDNF Gene Expression Levels in Unpredictable Chronic Mild Stress (UCMS)-Exposed Mice [J] . Esen Gumuslu, Oguz Mutlu, Deniz Sunnetci, Drug Target Insights . 2014,第8期

机译：抗抑郁剂Agomelatine改善了不可预测的慢性轻度应激（UCMS）暴露小鼠的记忆力衰退并上调了CREB和BDNF基因表达水平
4. Antidepressant-like activity of agomelatine in the mouse unpredictable chronic mild stressed model [C] . Mutlu O., Ulak G., Gumuslu E., European Congress of Pharmacology . 2012

机译：在小鼠不可预测的慢性轻度胁迫模型中抗抑郁的致癌物活性
5. Alterations of the corticotropin-releasing hormone receptor system following early life stress and chronic ethanol selfadministration in rhesus monkeys [D] . Trimnal, Megan Waddell 2011

机译：恒河猴早期生活压力和慢性乙醇自我给药后促肾上腺皮质激素释放激素受体系统的变化
6. The Antidepressant Agomelatine Improves Memory Deterioration and Upregulates CREB and BDNF Gene Expression Levels in Unpredictable Chronic Mild Stress (UCMS)-Exposed Mice [O] . Esen Gumuslu, Oguz Mutlu, Deniz Sunnetci, 2014

机译：抗抑郁剂Agomelatine改善了不可预测的慢性轻度应激（UCMS）暴露小鼠的记忆力衰退并上调了CREB和BDNF基因表达水平
7. Increased expression level of corticotropin-releasing hormone in the amygdala and in the hypothalamus in rats exposed to chronic unpredictable mild stress [O] . Wang, Shan-Shan, Yan, Xue-Bo, Hofman, Michel A., 2010

机译：慢性不可预测的轻度应激大鼠杏仁核和下丘脑中促肾上腺皮质激素释放激素的表达水平增加

Increased expression level of corticotropin-releasing hormone in the amygdala and in the hypothalamus in rats exposed to chronic unpredictable mild stress

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