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Long-Term Hearing Outcome After Retrosigmoid Removal of Vestibular Schwannoma

机译:切除前庭神经鞘瘤后乙状结肠的长期听力结果

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摘要

Although many investigators have reported the hearing function in the immediate postoperative period in patients with vestibular schwannoma (VS), little is known about the long-term outcomes of the postoperative hearing. The aim of this study was to analyze the long-term hearing outcomes at a mean follow-up of 5 years in patients with unilateral VS treated via the retrosigmoid approach. Twenty-four patients with immediate postoperative serviceable hearing who underwent repeated audiogram or phone interview were included in this study. During the mean follow-up period (68.8 ± 30.2 months, range 14–123 months), serviceable hearing was preserved in 20 out of the 24 patients (83%). Pure tone average (PTA) was reevaluated within 6 months in seven patients. In the two patients whose PTA deteriorated ≥ 5 dB in 6 months after surgery, their PTA worsened ≥ 15 dB compared to the immediate postoperative PTA. In the remaining five patients whose PTA deteriorated < 5 dB in 6 months after surgery, PTA was maintained within a 15-dB deterioration at the final follow-up (p = 0.04, Fisher's exact test). According to Kaplan–Meier survival plots, the 5-year or 7-year preservation rate of serviceable hearing was 86.2% or 71.8%, respectively. Further study will be needed to clarify the mechanism underlying the long-term decline of serviceable hearing; however, the deterioration of PTA in the early postoperative period may help to predict the long-term outcomes of hearing.
机译:尽管许多研究者已经报告了前庭神经鞘瘤(VS)患者术后即刻的听力功能,但对术后听力的长期预后知之甚少。这项研究的目的是分析通过乙状结肠后入路治疗的单侧VS患者平均5年的长期随访结果。这项研究包括了二十四例接受了术后可立即听诊的患者,他们接受了反复的听力图或电话采访。在平均随访期间(68.8±30.2个月,范围14-123个月),24例患者中有20例保留了可服务的听力(83%)。 7名患者在6个月内重新评估了纯音平均(PTA)。在术后6个月内PTA恶化≥5 dB的两名患者中,与即刻术后PTA相比,他们的PTA恶化≥15 dB。其余5例术后6个月PTA恶化<5 dB的患者,在最后的随访中PTA维持在15 dB恶化之内(p = 0.04,Fisher精确检验)。根据Kaplan–Meier生存图,可服务听力的5年或7年保存率分别为86.2%或71.8%。需要进一步研究,以澄清可服务听力长期下降的潜在机制;然而,术后早期PTA的恶化可能有助于预测听力的长期结果。

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