MBCL-26. EFFECTIVE MANAGEMENT OF MEDULLOBLASTOMA WITH 2 D CONVENTIONAL MODALITY IN CURRENT ERA OF MODERN TECHNOLOGY – OUR INSTITUTIONAL EXPERIENCE

摘要

Medulloblastoma is a common CNS tumour in pediatric age group. Post- operative craniospinal irradiation (CSI) with concurrent and adjuvant chemotherapy is the standard approach of the treatment. In current era, Tomotherapy and Proton therapy are very promising modalities. But these modalities are still less available in developing countries. We have treated 51 patients of medulloblastoma with conventional 2D modality. A total 41 patients are on regular follow-up. 76% (n= 31) patients were pediatric and adolescent age group. All the patients were treated in supine position. We have evaluated 31 patients for treatment feasibility, patient compliance, acute reactions and short-term outcome. Patient compliance was 100%. Five patients (16.1%) had acute reactions in the form of ulcers over tip of tongue and neutropenia and were managed conservatively. Two of the patients (6.4%) developed recurrence within 1 to 2 yrs of treatment. Twenty-five patients (80.6%) are asymptomatic till date. Four patients (12.9%) died within 1 year of primary treatment because of different reasons.CONCLUSIONWith proper planning and management, medulloblastoma can be treated successfully with 2D external beam radiotherapy with promising results and acceptable acute toxicities even at the centres where the modern technologies are not available. Long term follow-up is required for disease free and 5-year overall survival data.