Phase II Study to Topotecan and Cisplatin in Advanced Hepatocellular Carcinoma

机译：晚期肝细胞癌托泊替康和顺铂的II期研究

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摘要

Background:Hepatocellular carcinoma remains a highly chemoresistant neoplasm and is a common malignancy with poor prognosis in Korea. We performed a phase II study to evaluate the efficacy and toxicities of topotecan and cisplatin combination chemotherapy for advanced hepatocellular carcinoma.

机译：背景：肝细胞癌仍是高度化学耐药的肿瘤，是韩国常见的恶性肿瘤，预后较差。我们进行了II期研究，以评估拓扑替康和顺铂联合化疗对晚期肝细胞癌的疗效和毒性。

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期刊名称 The Korean Journal of Internal Medicine
作者
Ga Young Lee; Bong-Seog Kim; Yeoung Tae Seo; Seong Ho Choi; Hye Jin Kim; Dong Seog Choi; Ji Young Ko; Soo Hyun Yang; Jong Hoon Byun;
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作者单位

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年(卷),期 2003(18),2
年度 2003
页码 104–108
总页数 5
原文格式 PDF
正文语种
中图分类基础医学;
关键词
Carcinoma Hepatocellular Topotecan Cisplatin;

机译：癌;肝细胞癌;托泊替康;顺铂;

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专利

1. Quality of life outcomes from a randomized phase III trial of cisplatin with or without topotecan in advanced carcinoma of the cervix: a Gynecologic Oncology Group Study. [J] . Monk BJ, Huang HQ, Cella D, Journal of Clinical Oncology . 2005,第21期

机译：子宫颈癌晚期有或没有托泊替康的顺铂III期随机临床试验的生活质量结果：妇科肿瘤小组研究。
2. Weekly topotecan and cisplatin (TOPOCIS) as neo-adjuvant chemotherapy for locally-advanced squamous cervical carcinoma: Results of a phase II multicentric study [J] . ZanaboniF., GrijuelaB., GiudiciS., European journal of cancer: official journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR) . 2013,第5期

机译：每周拓扑替康和顺铂（TOPOCIS）作为局部晚期鳞状上皮癌的新辅助化疗：II期多中心研究的结果
3. Phase II feasibility study of sequential couplets of Cisplatin/Topotecan followed by paclitaxel/cisplatin as primary treatment for advanced epithelial ovarian cancer: a National Cancer Institute of Canada Clinical Trials Group Study. [J] . Hoskins P, Eisenhauer E, Vergote I, Journal of Clinical Oncology . 2000,第24期

机译：顺铂/托泊替康序贯对联，然后紫杉醇/顺铂作为晚期上皮性卵巢癌的主要治疗方法的II期可行性研究：加拿大国家癌症研究所临床试验小组研究。
4. Molecular Therapies in Hepatocellular Carcinoma beyond Sorafenib: Lessons from Failed Phase III Trials and Novel Targets [C] . Lipika Goyal, Andrew X. Zhu Gastrointestinal Cancers Symposium . 2014

机译：Sorafenib之外的肝细胞癌中的分子疗法：III期试验失败的课程和新型靶标
5. Comparison of linear, bi-dimensional and volumetric measurements in evaluating tumor response of Hepatocellular carcinoma lesions in the arterial and portal venous phases on MRI. [D] . Pratt, Michelle Sherman. 2015

机译：在MRI上评估动脉，门静脉期肝细胞癌病变的线性，二维和体积测量结果的比较。
6. Sorafenib plus hepatic arterial infusion chemotherapy with cisplatin versus sorafenib for advanced hepatocellular carcinoma: randomized phase II trial [O] . M. Ikeda, S. Shimizu, T. Sato, -1

机译：索拉非尼联合肝动脉灌注化疗联合顺铂与索拉非尼治疗晚期肝细胞癌：II期随机试验
7. Advanced Ovarian Cancer: Phase III Randomized Study of Sequential Cisplatin–Topotecan and Carboplatin–Paclitaxel vs Carboplatin–Paclitaxel [O] . P. Hoskins, I. Vergote, A. Cervantes, 2010

机译：先进的卵巢癌：III期随机研究顺铂 - 拓扑替替康和卡铂 - 紫杉醇与Carboplatin-PACLitaxel

Phase II Study to Topotecan and Cisplatin in Advanced Hepatocellular Carcinoma

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