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Correlation Between High-Density Lipoprotein and Monocyte Subsets in Patients with Stable Coronary Heart Disease

机译:稳定型冠心病患者高密度脂蛋白与单核细胞亚群的相关性

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摘要

BackgroundHigh-density lipoprotein (HDL) consists of heterogeneous particles with a variety of structures and functions. Its role in atherosclerosis has been gradually recognized. Studies have shown dysfunction of small HDL in patients with coronary artery disease (CAD). Monocytes play an important role in atherosclerosis, which can be divided into 3 subgroups based on the expression of surface markers CD14 and CD16. This study aimed to investigate the association between HDL and monocyte subsets in CAD patients.
机译:背景高密度脂蛋白(HDL)由具有各种结构和功能的异质颗粒组成。它在动脉粥样硬化中的作用已被逐渐认识到。研究表明,患有冠状动脉疾病(CAD)的患者存在小HDL的功能障碍。单核细胞在动脉粥样硬化中起重要作用,根据表面标记CD14和CD16的表达可将其分为3个亚组。这项研究旨在调查CAD患者中HDL与单核细胞亚群之间的关联。

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