Genetic risk score (GRS) constructed from polymorphisms in the PON1 IL-6 ITGB3 and ALDH2 genes is associated with the risk of coronary artery disease in Pakistani subjects

摘要

BackgroundCoronary artery disease (CAD) is a major killer in today’s world. Pakistan is also affected by this non-communicable disease like other countries. It is a multifactorial disease and is influenced by many gene-gene and gene-environment interactions.