A 77-year-old female with a subacute progression of ataxia and serum anti-Yo antibodies was suspected to have paraneoplastic cerebellar degeneration (PCD). An examination of an underlying cancer showed no abnormality in the gynecological organs, but the findings did show a mass in the Douglas fossa. The mass was resected and diagnosed as stage IIB peritoneal serous papillary carcinoma (PSPC), a rare gynecologic cancer that is difficult to diagnose in the early stages. PCD was treated with intravenous immunoglobulin (IVIG). For an early diagnosis and treatment, PSPC should be included in the list of malignancies that cause PCD with anti-Yo antibodies.
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机译:一名 77 岁女性,共济失调和血清抗 Yo 抗体亚急性进展,疑似副肿瘤性小脑变性 (PCD)。对潜在癌症的检查显示妇科器官没有异常,但结果确实显示道格拉斯窝有肿块。切除肿块并诊断为 IIB 期腹膜浆液性状癌 (PSPC),这是一种罕见的妇科癌症,早期难以诊断。用静脉注射免疫球蛋白 (IVIG) 治疗 PCD。为了早期诊断和治疗,PSPC 应包含在具有抗 Yo 抗体的导致 PCD 的恶性肿瘤列表中。
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