Lymphoma-targeted treatment using a folic acid-decorated vincristine-loaded drug delivery system

机译：叶酸修饰的长春新碱载药系统对淋巴瘤的治疗

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PurposeB-cell lymphoma is the most frequently diagnosed lymphoid tumor. Folic acid (FA)-decorated systems were found to be preferentially internalized on the B-cell lymphoma cell line which is reported to express the folate receptor. This study was designed to develop an FA-decorated vincristine (VCR)-loaded system for targeted lymphoma treatment.

机译：目的B细胞淋巴瘤是最常被诊断的淋巴样肿瘤。发现叶酸（FA）修饰的系统优先内在B细胞淋巴瘤细胞系中，据报道该细胞表达叶酸受体。这项研究旨在开发一种带有FA装饰的长春新碱（VCR）的系统，用于靶向淋巴瘤治疗。

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期刊名称 Drug Design Development and Therapy
作者
Lei Qiu; Chao Dong; Xuan Kan;
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作者单位

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年(卷),期 2018(12),-1
年度 2018
页码 863–872
总页数 10
原文格式 PDF
正文语种
中图分类药学;药物化学;
关键词
lymphoma drug delivery system lipid-polymer hybrid nanoparticles folic acid vincristine;

机译：淋巴瘤;药物递送系统;脂质-聚合物杂化纳米颗粒;叶酸;长春新碱;

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专利

1. Lymphoma-targeted treatment using a folic acid-decorated vincristine-loaded drug delivery system [J] . Lei Qiu, Chao Dong, Xuan Kan Drug Design, Development and Therapy . 2018,第InaProgress期

机译：使用叶酸修饰的长春新碱载药递送系统进行淋巴瘤靶向治疗
2. Environmentally friendly, one-pot synthesis of folic acid-decorated graphene oxide-based drug delivery system [J] . Quankui Lin, Xiaojie Huang, Junmei Tang, Journal of nanoparticle research: An interdisciplinary forum for nanoscale science and technology . 2013,第12期

机译：基于环境的一锅法合成叶酸修饰的氧化石墨烯基药物递送系统
3. Sonochemical preparation of folic acid-decorated reductive-responsive ε-poly-L-lysine-based microcapsules for targeted drug delivery and reductive-triggered release [J] . Shi Chao, Zhong Shuangling, Sun Yuexin, Materials science & engineering . 2020,第Jana期

机译：声化学法制备叶酸修饰的还原反应型ε-聚L-赖氨酸基微胶囊，用于靶向药物递送和还原触发释放
4. Folic acid-conjugated amphiphilic star-like macromolecules (FA-ASMs) as a targeted anti-cancer drug delivery system [C] . Controlled Release Society annual meeting . 2004

机译：叶酸 - 缀合的两亲星形致马发（FA-ASM）作为靶向抗癌药物递送系统
5. Engineering targeted drug delivery systems for the treatment of triple negative breast cancer [D] . Jadia, Rahul 2018

机译：工程靶向药物输送系统，用于治疗三阴性乳腺癌
6. Folic Acid-Terminated Poly(2-Diethyl Amino Ethyl Methacrylate) Brush-Gated Magnetic Mesoporous Nanoparticles as a Smart Drug Delivery System [O] . Abeer M. Beagan, Ahlam A. Alghamdi, Shatha S. Lahmadi, 2021

机译：叶酸封端的聚（2-二乙基氨基甲基丙烯酸酯）刷涂磁性介孔纳米粒子作为智能药物递送系统
7. Lymphoma-targeted treatment using a folic acid-decorated vincristine-loaded drug delivery system [O] . Lei Qiu, Chao Dong, Xuan Kan 2018

机译：淋巴瘤 - 靶向治疗使用叶酸装饰的长春脉加载的药物递送系统

Lymphoma-targeted treatment using a folic acid-decorated vincristine-loaded drug delivery system

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