Folic acid-conjugated amphiphilic star-like macromolecules (FA-ASMs) as a targeted anti-cancer drug delivery system

摘要

Folic acid-conjugated amphiphilic star-like macromolecules (FA-ASMs) were synthesized and evaluated in terms of their drug encapsulation ability and cytotoxicity. Drug loading studies showed that doxorubicin can be successfully incorporated into the micelles, whereas cytototoxicity studies revealed that FA-ASMs didn't show significant cytotoxicity up to concentration of 0.0001 mM.