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Core decompression for early-stage avascular necrosis of the humeral head: current concepts and techniques

机译:早期肱骨头缺血性坏死的核心减压术:当前的概念和技术

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摘要

Avascular necrosis (AVN) of the humeral head is a rare, yet detrimental complication. Left untreated, humeral head AVN frequently progresses to subchondral fracturing and articular collapse. Cases of late-stage humeral head AVN commonly require invasive procedures including humeral head resurfacing, hemiarthroplasty, and total shoulder arthroplasty (TSA) to improve clinical outcomes. However, in cases of early-stage AVN, core decompression of the humeral head is a viable and efficacious short-term treatment option for patients with pre-collapse AVN of the humeral head to improve clinical outcomes and prevent disease progression. Several techniques have been described, however, a percutaneous, arthroscopic-assisted technique may allow for accurate staging and concomitant treatment of intraarticular pathology during surgery, although further long-term clinical studies are necessary to assess its overall outcomes compared with standard techniques. Biologic adjunctive treatments, including synthetic bone grafting, autologous mesenchymal stem cell/bone marrow grafts, and bone allografts are viable options for reducing the progression of AVN to further collapse in the short term, although long-term follow-up with sufficient study power is lacking in current clinical studies. Further long-term outcome studies are required to determine the longevity of core decompression as a conservative measure for early-stage AVN of the humeral head.
机译:肱骨头缺血性坏死 (AVN) 是一种罕见但有害的并发症。如果不及时治疗,肱骨头 AVN 经常进展为软骨下骨折和关节塌陷。晚期肱骨头 AVN 病例通常需要侵入性手术,包括肱骨头表面置换术、半关节置换术和全肩关节置换术 (TSA),以改善临床结果。然而,在早期 AVN 病例中,对于肱骨头塌陷前 AVN 患者来说,肱骨头核心减压是一种可行且有效的短期治疗选择,可改善临床结局并防止疾病进展。已经描述了几种技术,然而,经皮关节镜辅助技术可能允许在手术过程中对关节内病变进行准确分期和伴随治疗,尽管与标准技术相比,需要进一步的长期临床研究来评估其总体结果。生物辅助治疗,包括合成骨移植、自体间充质干细胞/骨髓移植和同种异体骨移植是短期内减少 AVN 进展进一步崩溃的可行选择,尽管目前的临床研究缺乏具有足够研究把握度的长期随访。需要进一步的长期结局研究来确定核心减压作为早期肱骨头 AVN 保守措施的寿命。

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