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Applying a cumulative risk framework to drinking water assessment: a commentary

机译:将累积风险框架应用于饮用水评估:评论

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摘要

The health risks of drinking water contaminants and the economic benefits of drinking water standards are typically assessed one chemical at a time, an approach that misses the health impacts of co-occurring contaminants in drinking water. In contrast, a cumulative risk framework has become common in air quality evaluations such as the U.S. Environmental Protection Agency’s National Air Toxics Assessment. We posit that the drinking water field would benefit from making the transition to a unified assessment framework for multiple contaminants that can overcome the long-standing challenge of treating cancer and non-cancer contaminants separately. Here we present a cumulative risk methodology that combines a risk-based cancer metric with a weighted health indicator index for non-cancer contaminants and incorporates disability weights from the Global Burden of Disease study. Our methodology generates a numeric toxicity score reflecting the potential health impacts for the sum of contaminants present in each sample of drinking water. Further research is needed to refine the risk and toxicity parameters for specific contaminants and to address the mode of interaction between co-occurring chemicals. As this cumulative risk model goes through future refinements, we anticipate that it would provide information that can help communities and policy makers evaluate different options for drinking water treatment.Electronic supplementary materialThe online version of this article (10.1186/s12940-019-0475-5) contains supplementary material, which is available to authorized users.
机译:饮用水污染物的健康风险和饮用水标准的经济效益通常是一次评估一种化学物质,这种方法忽略了饮用水中同时存在的污染物对健康的影响。相比之下,累积风险框架已在空气质量评估(例如美国环境保护局的国家空气毒性评估)中变得很普遍。我们假设饮用水领域将受益于向多种污染物的统一评估框架的转变,该框架可以克服长期以来分别治疗癌症和非癌症污染物的挑战。在这里,我们介绍了一种累积风险方法,将基于风险的癌症指标与非癌症污染物的加权健康指标指数相结合,并纳入了全球疾病负担研究中的残疾权重。我们的方法生成了一个数字毒性评分,该评分反映了每个饮用水样品中所含污染物总量对健康的潜在影响。需要进一步的研究来完善特定污染物的风险和毒性参数,并解决共生化学物质之间相互作用的方式。随着这种累积风险模型的不断完善,我们预计它将提供信息,以帮助社区和决策者评估饮用水处理的不同选择。电子补充材料本文的在线版本(10.1186 / s12940-019-0475-5 )包含补充材料,授权用户可以使用。

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