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The influence of DNA polymorphism of multidrug resistant 1 (MDR1) on the effect of midazolam pretreatment in children

机译：儿童多药耐药1（MDR1）DNA多态性对咪达唑仑预处理的影响

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摘要

BackgroundPatients showed a different response following intravenous midazolam injection. Some children showed irritability or were not sedated by midazolam. We hypothesized that there may be genetic variations of the MDR1 gene, based on the response to midazolam.

机译：背景静脉注射咪达唑仑后患者表现出不同的反应。一些孩子表现出烦躁或没有被咪达唑仑镇静。我们假设基于对咪达唑仑的反应，MDR1基因可能存在遗传变异。

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期刊名称 Korean Journal of Anesthesiology
作者
Hyo-Jin Byon; Keun-Suk Park; Yong-Hee Park; Jin-Tae Kim; Chul-Woo Jung; Hee-Soo Kim;
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作者单位

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年(卷),期 2012(62),4
年度 2012
页码 332–336
总页数 5
原文格式 PDF
正文语种
中图分类麻醉学 ; 麻醉学 ;
关键词
Genetic polymorphism MDR1 Midazolam;

机译：遗传多态性;MDR1;咪达唑仑;

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1. The drug-transporter gene MDR1 C3435T and G2677T/A polymorphisms and the risk of multidrug-resistant epilepsy in Turkish children [J] . Seven Mehmet, Batar Bahadir, Unal Selin, Molecular biology reports . 2014 ,第1期

机译：土耳其儿童中的药物转运蛋白基因MDR1 C3435T和G2677T / A多态性和多药耐药性癫痫的风险
2. The association between MDR1 C3435T genetic polymorphism and the risk of multidrug-resistant epilepsy in Egyptian children [J] . Elmagid Dina Salama Abd, Abdelsalam Maha, Magdy Hend, Egyptian Journal of Medical Human Genetics . 2021 ,第1期

机译：埃及儿童MDR1 C3435T遗传多态性与多药抗癫痫的风险
3. Multidrug resistance 1 (MDR1) gene polymorphisms in childhood drug-resistant epilepsy. [J] . Alpman A, Ozkinay F, Tekgul H, Journal of child neurology . 2010 ,第12期

机译：儿童耐药性癫痫中的多药耐药性1（MDR1）基因多态性。
4. Polymorphisms of Pvmdr1 gene associated with Chloroquine Resistance Phenotype among Plasmodium vivax isolates in Indonesia [C] . Asih PBS, Sadikin M, Baird JK, International Congress of Parasitology . 2010

机译：与印度尼西亚疟原虫分离株中氯喹耐药表型相关PVMDR1基因的多态性
5. In vitro Transport Profile of Antiepileptic Drugs by Human P-glycoprotein and Functional Evaluation of Human MDR1 Polymorphisms on Transport Activity. [D] . Zhang, Chunbo. 2011

机译：抗癫痫药通过人P糖蛋白的体外转运谱和人MDR1多态性对转运活性的功能评估。
6. The drug-transporter gene MDR1 C3435T and G2677T/A polymorphisms and the risk of multidrug-resistant epilepsy in Turkish children [O] . Mehmet Seven, Bahadir Batar, Selin Unal, -1

机译：土耳其儿童中的药物转运蛋白基因MDR1 C3435T和G2677T / A多态性和多药耐药性癫痫的风险
7. The influence of DNA polymorphism of multidrug resistant 1 (MDR1) on the effect of midazolam pretreatment in children [O] . Byon, Hyo-Jin, Park, Keun-Suk, Park, Yong-Hee, 2012

机译：儿童多药耐药1（MDR1）DNA多态性对咪达唑仑预处理的影响

The influence of DNA polymorphism of multidrug resistant 1 (MDR1) on the effect of midazolam pretreatment in children

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