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Cholangiographic Features in the Diagnosisand Management of Obstructive IctericType Hepatocellular Carcinoma

机译:诊断中的胆道功能梗阻性黄疸的治疗与治疗肝细胞癌

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摘要

In 11 years and 3 months, 2037 patients with HCC were seen and 48 patients (2.4%) were diagnosed to have obstructive icteric type HCC. Five patients were terminally ill and were not investigated further. Forty three patients were initially investigated by endoscopic retrograde cholangiography (ERC) or percutaneous transhepatic cholangiogram (PTC) and classified as having obstructive icteric type 1, 2, or 3 HCC based on the cholangiographic findings. The obstruction in type 1 HCC was due to intraluminal tumour casts and/or tumour fragments obstructing the hepatic ductal confluence or common bile duct, while intraluminal blood clots, from haemobilia, filling the biliary tree was the cause in type 2 HCC. The pathology in type 3 HCC was extraluminal obstruction by extensive tumour encasement of the intra–hepatic biliary ductal system and/or extrinsiccompression of the hepatic and common bile ductsby tumour(s) and/or malignant lymph nodes. Atthe initial ERC/PTC, 10 patients (5 resected, 50%)had obstructive icteric type 1 and 23 patients (0 resected)had obstructive icteric type 3 HCC. Of the 10patients initially classified according to cholangiographyto have obstructive icteric type 2 HCC,subsequent investigations revealed that 6 patientshad type 1 HCC (4 resectable, 67%) and 4 patientshad type 3 HCC (0 resectable). The classification ofthe obstructive icteric type HCC into types 1, 2, and3, based on the initial cholangiographic appearanceshas simplified and rationalized our managementstrategy for this condition.
机译:在11年零3个月内,共观察到2037例HCC患者,其中48例(2.4%)被诊断为梗阻性黄疸型HCC。五名患者绝症,不再进一步调查。最初对43例患者进行了内窥镜逆行胆管造影(ERC)或经皮肝穿刺胆管造影(PTC)的检查,根据胆管造影的发现将其分类为阻塞性黄疸型1、2或3型HCC。 1型HCC的阻塞是由于管腔内的肿瘤铸型和/或肿瘤碎片阻塞了肝管汇合或胆总管,而2型HCC的原因是来自血管内皮的血凝块填充胆道树。 3型HCC的病理是肝内胆管系统和/或外源性肿瘤广泛包埋而引起管腔外阻塞压缩肝和胆总管通过肿瘤和/或恶性淋巴结。在最初的ERC / PTC,10例(5例,50%)有梗阻性黄疸1型和23例(0切除)患有阻塞性黄疸3型肝癌。在10中最初根据胆道造影分类的患者患有阻塞性黄疸2型肝癌,随后的调查显示,有6名患者患有1型HCC(4例可切除,占67%)和4例患者拥有3型HCC(0可切除)。分类将梗阻性黄疸型HCC分为1型,2型和3,根据最初的胆道造影表现简化和合理化了我们的管理针对这种情况的策略。

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