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The effect of analytical temperature on thromboelastography tracings in dogs

机译:分析温度对狗血栓弹力图描记的影响

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摘要

Viscoelastic testing methods such as thromboelastography (TEG) are becoming increasingly available to veterinarians in a clinical setting. TEG is useful in determining therapeutic transfusion needs and assessing global abnormalities of hemostasis of patients, given that it provides a more comprehensive assessment of coagulation than traditional tests. TEG is standardly performed at 37°C, which is considered a normal body temperature for human patients; however, 37°C is lower than normal body temperature for most canine patients. In an in vitro study, we investigated the potential effect that this difference in body temperature and test temperature might have on TEG results. Citrated blood samples were collected from clinically normal, as well as sick, dogs with various body temperatures. Samples were analyzed concurrently at the patient’s body temperature and at 37°C. There was very high correlation between TEG performed at body temperature and at 37°C for R (min) and MA (mm), high correlation for K (min) and alpha angle (deg), and moderate correlation for LY30 (%) and LY60 (%). For canine patients with normal to mildly abnormal body temperatures, performance of TEG at the standard 37°C is acceptable.
机译:血栓弹力图 (TEG) 等粘弹性检测方法正越来越多地被临床中的兽医所使用。TEG 可用于确定治疗性输血需求和评估患者止血的整体异常,因为它比传统检查提供更全面的凝血评估。TEG 在 37°C 下标准进行,这被认为是人类患者的正常体温;然而,37°C 低于大多数犬类患者的正常体温。在一项体外研究中,我们调查了体温和测试温度的差异可能对 TEG 结果产生的潜在影响。从临床正常以及具有不同体温的生病狗中收集柠檬酸盐血样。在患者体温和 37°C 下同时分析样本。 在体温和 37°C 下进行的 TEG 对 R (min) 和 MA (mm) 的相关性非常高,K (min) 和 α 角 (deg) 的相关性很高,LY30 (%) 和 LY60 (%) 的相关性中等。对于体温正常至轻度异常的犬类患者,TEG 在标准 37°C 下的性能是可以接受的。

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