首页> 美国卫生研究院文献>The Indian Journal of Medical Research >Modulatory effect of polyphenolic extracts of Ichnocarpus frutescens on oxidative stress in rats with experimentally induced diabetes
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Modulatory effect of polyphenolic extracts of Ichnocarpus frutescens on oxidative stress in rats with experimentally induced diabetes

机译:藜果多酚提取物对实验性糖尿病大鼠氧化应激的调节作用

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摘要

Background & objectives:The role of oxidative stress in the development of diabetes mellitus and its vascular complications are extensively studied. Hyperglycaemia causes oxidative damage by generation of reactive oxygen species and results in the development of complications. The present study was undertaken with the objective of exploring the anti-hyperglycaemic potential of polyphenolic enriched extract of Ichnocarpus frutescens in streptozotocin induced (n-STZ) neonatal diabetic rats (pups) for six weeks and to study oxidative stress and antioxidant status.
机译:背景与目的:广泛研究氧化应激在糖尿病及其血管并发症中的作用。高血糖症通过产生活性氧而导致氧化损伤,并导致并发症的发展。进行本研究的目的是探索富含多酚的Ichnocarpus frutescens多酚提取物在链脲佐菌素诱导的(n-STZ)新生糖尿病大鼠(幼崽)中的降血糖潜力,并研究其氧化应激和抗氧化状态。

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