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Increased Biocompatibility and Bioactivity after Energetic PVD Surface Treatments

机译:能量PVD表面处理后提高的生物相容性和生物活性

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摘要

Ion implantation, a common technology in semiconductor processing, has been applied to biomaterials since the 1960s. Using energetic ion bombardment, a general term which includes conventional ion implantation plasma immersion ion implantation (PIII) and ion beam assisted thin film deposition, functionalization of surfaces is possible. By varying and adjusting the process parameters, several surface properties can be attuned simultaneously. Extensive research details improvements in the biocompatibility, mainly by reducing corrosion rates and increasing wear resistance after surface modification. Recently, enhanced bioactivity strongly correlated with the surface topography and less with the surface chemistry has been reported, with an increased roughness on the nanometer scale induced by self-organisation processes during ion bombardment leading to faster cellular adhesion processes.
机译:自1960年代以来,离子注入是半导体加工中的一种常用技术,已应用于生物材料。使用高能离子轰击(包括常规离子注入,等离子浸入式离子注入(PIII)和离子束辅助薄膜沉积的通用术语),可以实现表面功能化。通过改变和调整工艺参数,可以同时调整几种表面性能。广泛的研究详细介绍了生物相容性的改进,主要是通过降低腐蚀速率和提高表面改性后的耐磨性。近来,已经报道了增强的生物活性与表面形貌密切相关,而与表面化学的相关性较小,在离子轰击过程中由自组织过程诱导的纳米级粗糙度增加,导致更快的细胞粘附过程。

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