The impact of prothrombin complex concentrates when treating DOAC-associated bleeding: a review

机译：凝血酶原复合物浓缩物在治疗DOAC相关性出血时的作用：综述

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BackgroundBleeding complications are a risk associated with all anticoagulants. Currently, the treatment options for the management of direct oral anticoagulant (DOAC)-associated bleeding are limited. Prothrombin complex concentrates (PCCs) have been proposed as a potential therapeutic option, and evidence regarding their use is increasing.

机译：背景出血并发症是与所有抗凝剂相关的风险。当前，用于治疗直接口服抗凝剂（DOAC）相关性出血的治疗选择有限。凝血酶原复合物浓缩物（PCCs）已被提出作为潜在的治疗选择，并且关于其使用的证据正在增加。

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期刊名称 International Journal of Emergency Medicine
作者
Maureane Hoffman; Joshua N. Goldstein; Jerrold H. Levy;
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作者单位

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年(卷),期 2018(11),-1
年度 2018
页码 55
总页数 18
原文格式 PDF
正文语种
中图分类基础医学;
关键词
Anticoagulants Haemorrhage Non-vitamin K antagonist oral anticoagulants Dabigatran Rivaroxaban Edoxaban Apixaban Prothrombin complex concentrates Anticoagulant reversal;

机译：抗凝剂;出血;非维生素K拮抗剂口服抗凝剂;达比加群;利伐沙班;依多沙班;阿哌沙班;凝血酶原复合浓缩物;抗凝剂逆转;

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专利

1. The impact of prothrombin complex concentrates when treating DOAC-associated bleeding: a review [J] . Maureane Hoffman, Joshua N. Goldstein, Jerrold H. Levy International Journal of Emergency Medicine . 2018,第1期

机译：治疗Doac相关出血时凝血酶素复合物浓缩物的影响：综述
2. Effectiveness of prothrombin complex concentrate (PCC) in neonates and infants with bleeding or risk of bleeding: a systematic review and meta-analysis [J] . Zeng Linan, Choonara Imti, Zhang Lingli, European journal of pediatrics . 2017,第5期

机译：凝血酶体复合物浓缩物（PCC）在新生儿和婴儿出血或出血风险的疗效：系统评价和荟萃分析
3. Efficacy and safety of prothrombin complex concentrate in patients treated with rivaroxaban or apixaban compared to warfarin presenting with major bleeding [J] . Arachchillage Deepa R. J., Alavian Sharon, Griffin Jessica, British Journal of Haematology . 2019,第5期

机译：用大型出血的丙糖兰蛋白或阿列西西克兰治疗的患者中凝血酶体复合物浓缩物的疗效和安全性
4. LEACHING OF BULK FLOTATION CONCENTRATE AS AN ALTERNATIVE TO TREAT A COMPLEX SULFIDE ORE [C] . C.A. Sosa-Blanco, C. Lara-Valenzuela International Copper-Cobre Conference . 2007

机译：散装浮选的浸出浓缩，作为治疗复合硫化物矿石的替代品
5. Reversal of Warfarin-Associated Coagulopathy: Prothrombin Complex Concentrates Versus Fresh Frozen Plasma in Elderly Patients Presenting with Intracranial Hemorrhage [D] . Lumas, Shunella Grace. 2020

机译：逆转华法林相关凝血病：凝血酶原浓缩物与颅内出血患者的老年患者新鲜冷冻血浆
6. Clinical outcome of patients with a vitamin K antagonist‐associated bleeding treated with prothrombin complex concentrate [O] . Marjolein P. A. Brekelmans, Rahat A. Abdoellakhan, Luuk J. J. Scheres, 2018

机译：凝血酶原复合浓缩物治疗维生素K拮抗剂相关性出血的患者的临床结局
7. 64 Health Care Costs in Direct-acting Oral Anticoagulant Major Bleeding Treated with 4-factor Prothrombin Complex Concentrate and Other Agents [O] . A.J. Singer, C.E. Mahan, K. McNeil-Posey, 2020

机译：64种医疗保健成本直接服用口服抗凝血剂重型出血，用4因素凝血酶浓缩物和其他药剂治疗

The impact of prothrombin complex concentrates when treating DOAC-associated bleeding: a review

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