首页> 美国卫生研究院文献>Current Controlled Trials in Cardiovascular Medicine >Evaluation of the safety and efficacy of XAV-19 in patients with COVID-19-induced moderate pneumonia: study protocol for a randomized double-blinded placebo-controlled phase 2 (2a and 2b) trial

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Evaluation of the safety and efficacy of XAV-19 in patients with COVID-19-induced moderate pneumonia: study protocol for a randomized double-blinded placebo-controlled phase 2 (2a and 2b) trial

机译：评估XAV-19在Covid-19诱导的中度肺炎患者中的安全性和功效：用于随机双盲安慰剂控制阶段2（2A和2B）试验的研究方案

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The online version contains supplementary material available at 10.1186/s13063-021-05132-9.

机译：在线版本包含10.1186 / S13063-021-05132-9的补充材料。

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期刊名称 Current Controlled Trials in Cardiovascular Medicine
作者
Benjamin Gaborit; Bernard Vanhove; Marie-Anne Vibet; Aurélie Le Thuaut; Karine Lacombe; Vincent Dubee; Florence Ader; Virginie Ferre; Eric Vicaut; Jéremie Orain; Morgane Le Bras; Anne Omnes; Laetitia Berly; Alexandra Jobert; Pascale Morineau-Le Houssine; Karine Botturi; Régis Josien; Laurent Flet; Nicolas Degauque; Sophie Brouard; Odile Duvaux; Alexandra Poinas; François Raffi; Eric Dailly; Thomas Guimard; Cécile Braudeau; Denis Malvy; Jean-François Faucher; Gabriela Illes Hajnal; Marc-Olivier Vareil; Mariam Roncato-Saberam; Laurent Vacher; Charlotte Biron; Maeva Lefebvre; Géraldine Gallot; Paul Le Turnier; Colin Deschanvres; Raphael Lecomte; Marie Chauveau; Anne-sophie Lecompte; Matthieu Grégoire; Ronan Bellouard; Guillaume Deslandes; Zineb Ouazene; Diane Bollens; Thibault Chiarabani; Jessica Krause-Le Garrec; Agathe Becker; Pierre Chauvelot; Anne Conrad; Tristan Ferry; Patrick Miailhes; Cécile Pouderoux; Sandrine Roux; Claire Triffault-Fillit;
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年(卷),期 2021(-1),-1
年度 2021
页码 -1
总页数 17
原文格式 PDF
正文语种
中图分类心血管疾病;
关键词
COVID-19; Anti-SARS-CoV-2 antibodies; Moderate pneumonia; Immunotherapy; Randomized controlled trial; Phase 2;

机译：Covid-19;抗SARS-COV-2抗体;中度肺炎;免疫疗法;随机对照试验;第2阶段;

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1. Evaluation of the safety and efficacy of XAV-19 in patients with COVID-19-induced moderate pneumonia: study protocol for a randomized, double-blinded, placebo-controlled phase 2 (2a and 2b) trial [J] . Benjamin Gaborit, Bernard Vanhove, Marie-Anne Vibet, Trials . 2021,第1期

机译：评估XAV-19患者Covid-19诱导的中度肺炎患者的安全性和功效：用于随机，双盲，安慰剂控制阶段2（2A和2B）试验的研究方案
2. A phase 2a randomized, double-blind, placebo-controlled, sequential dose-escalation study to evaluate the efficacy and safety of ASP015K, a novel Janus kinase inhibitor, in patients with moderate-to-severe psoriasis [J] . Papp K., Pariser D., Catlin M., British Journal of Dermatology . 2015,第3期

机译：2a期随机，双盲，安慰剂对照，序贯剂量递增研究，旨在评估新型Janus激酶抑制剂ASP015K在中至重度牛皮癣患者中的疗效和安全性
3. 012 Efficacy and Safety of Ixekizumab in a Randomized, Double-Blinded, Placebo-Controlled, Phase 3b Clinical Trial in Patients with Moderate-to-Severe Genital Psoriasis [J] . C. Ryan, A. Menter, L. Guenther, The journal of sexual medicine . 2018,第2期

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机译：中药配方CUF2在治疗儿童哮喘中的功效：动物实验，体外研究以及随机，双盲，安慰剂对照的临床试验。
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7. Pharmacokinetics and safety of XAV-19, a swine glyco-humanized polyclonal anti-SARS-CoV-2 antibody, for COVID-19-related moderate pneumonia: a randomized, double-blind, placebo-controlled, phase IIa study [O] . Benjamin Gaborit, Eric Dailly, Bernard Vanhove, 2021

机译：XAV-19的药代动力学和安全性，猪聚糖 - 人源化多克隆抗SARS-COV-2抗体，用于Covid-19相关的中度肺炎：随机，双盲，安慰剂控制，相IIA研究

Evaluation of the safety and efficacy of XAV-19 in patients with COVID-19-induced moderate pneumonia: study protocol for a randomized double-blinded placebo-controlled phase 2 (2a and 2b) trial

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