Immunohistological characterisation of tumour infiltrating lymphocytes in melanocytic skin lesions

摘要

BackgroundAlthough the presence of tumour infiltrating lymphocytes (TIL) is a constant feature in melanomas, their immunophenotypic characterisation is still incomplete. We hypothesise that the transition from normal skin to benign naevi (BN) to melanocytic dysplastic naevi (MDN) to radial growth phase cutaneous malignant melanoma (RGP‐CMM) to vertical growth phase cutaneous malignant melanoma (VGP‐CMM) is associated with alterations in TIL. This study attempted to test this hypothesis and to characterise TIL in the melanocytic skin lesions.