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Alternatives to hexachlorophene bathing of newborn infants.

机译:新生儿六氯酚沐浴的替代品。

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摘要

In controlled trials newborn infants were bathed with Lactacyd, pHisoHex, Hibitane, Lanohex or tap water. Bacteriologic samples were taken from three sites (groin, axilla and cord) immediately after birth, following an initial bath with one of the test agents, and on day 3 or 5 after a water bath. Initial bathing with all agents, including water, reduced the concentration of bacteria on the skin to a similar extent. However, comparisons of bacterial flora at birth versus those on days 3 and 5 indicated differences in the actions of the various agents on pathogenic and nonpathogenic organisms. Lactacyd and Hibitane appeared to be suitable alternatives to hexachlorophene in the control of pathogenic bacteria on the skin of newborns. However, their absorption and toxicity in the newborn are unknown and, unless use of a skin disinfectant is warranted, routine bathing of newborns with tap water appears to be satisfactory.
机译:在对照试验中,新生婴儿用乳酸,pHisoHex,Hibitane,Lanohex或自来水沐浴。出生后立即用三种测试剂(腹股沟,腋窝和脐带),用一种测试剂进行初次沐浴后以及水浴后的第3或5天从三个部位(腹股沟,腋窝和脐带)采集细菌学样品。最初使用所有试剂(包括水)进行沐浴,可将皮肤上细菌的浓度降低至相似程度。但是,比较出生时细菌菌群与第3天和第5天细菌菌群的比较表明,各种药剂对致病性和非致病性生物的作用有所不同。在控制新生儿皮肤上的致病细菌方面,乳酸菌和环戊烷似乎是六氯酚的合适替代物。但是,它们在新生儿中的吸收和毒性尚不明确,除非有必要使用皮肤消毒剂,否则用自来水对新生儿进行常规沐浴似乎令人满意。

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