In a study of the acid-base changes in the blood of rabbits during and following transfusions of citrated blood and of heparinized blood, it was observed that, with citrated blood, pH decreased and carbon dioxide tensions rose. With heparinized blood, the acid-base balance was maintained within normal limits following transfusions.The potential hazards of rapid massive citrated blood transfusions in the anesthetized patient during operation must be kept in mind.
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