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Biological monitoring of lead exposure in high risk groups in Berat Albania

机译:阿尔巴尼亚培拉特高危人群铅暴露的生物监测

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摘要

STUDY OBJECTIVE: To determine blood lead concentrations in children living in an area with a battery plant in Berat, Albania. Another aim was to determine blood lead concentrations in mothers and cord blood levels in neonates from Berat and compare them with values found in Tirana. DESIGN: Cross sectional survey with a 10% random sample of children, and a 10% sample of mothers and newborn. SETTING: Hospitals, schools, and kinder-gartens in Berat and Tirana, Albania PARTICIPANTS: 129 preschool children, 373 school children, 151 mothers and their newborn. MAIN RESULTS: The mean observed blood lead concentrations in 84 preschool children living less than 2 km from the battery plant was 43.4 micrograms/dl (SD 23.0) and significantly higher than in 45 preschool children (mean 15.0 micrograms/dl, SD 3.5) living more than 2 km from the plant. Mean lead concentrations in 145 school children living close to the plant were 26.6 micrograms/dl (SD 14.4) compared with 16.0 micrograms/dl in 228 school children living at a greater distance. In 67% of the preschool children and 41% of the school children lead levels exceeded the WHO borderline level of 20 micrograms/dl, and 98% of preschool children, and 82% of school children had values greater than 10 micrograms/dl. Mean lead concentrations in cord blood of 151 newborn was 8.9 micrograms/dl (median 8.8, range 4.9-20.0 micrograms/dl), and 10.6 micrograms/dl in blood of their mothers (median 10.0, range 5.0-25.4 micrograms/dl). Mean lead concentrations in Tirana were 8.9 (newborn), and 7.0 micrograms/dl (mothers). CONCLUSIONS: Blood lead concentrations in children from Berat are comparatively high and abatement measures are needed.  
机译:研究目的:确定居住在阿尔巴尼亚培拉特电池厂附近地区儿童的血铅浓度。另一个目的是确定来自培拉特的母亲的血铅浓度和新生儿的脐带血水平,并将其与地拉那的值进行比较。设计:横断面调查,随机抽取10%的儿童,抽取10%的母亲和新生儿。地点:阿尔巴尼亚培拉特和地拉那的医院,学校和幼稚园参与者:129名学龄前儿童,373名学龄儿童,151名母亲及其新生儿。主要结果:在距离电池厂不到2公里的84名学龄前儿童中观察到的平均血铅浓度为43.4微克/分升(标准差23.0),显着高于生活在45名学龄前儿童中(平均15.0微克/分升,标准差3.5)。距工厂2公里以上。靠近植物的145名学童的平均铅浓度为26.6微克/分升(标准差14.4),相比之下,住在更远距离的228名学校儿童的平均铅浓度为16.0微克/分升。在67%的学龄前儿童和41%的学龄儿童中,铅水平超过了WHO的临界值20微克/分升,而98%的学龄前儿童和82%的学龄儿童的铅值超过了10微克/分升。 151名新生儿的脐带血平均铅浓度为8.9微克/分升(中位数8.8,范围4.9-20.0微克/分升),母亲血液中的平均铅浓度为10.6微克/分升(中位数10.0,范围为5.0-25.4微克/分升)。地拉那的平均铅含量为8.9(新生儿)和7.0微克/ dl(母亲)。结论:培拉特州儿童的血铅浓度较高,需要采取减少措施。

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