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A multi-centre randomised phase III trial of Dexamethasone vs Dexamethasone and diethylstilbestrol in castration-resistant prostate cancer: immediate vs deferred Diethylstilbestrol

机译：地塞米松地塞米松和己烯雌酚治疗去势抵抗性前列腺癌的多中心随机III期试验：立即用己烯雌酚与延缓己烯雌酚

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摘要

Background: The role of further hormone therapy in castration-resistant prostate cancer (CRPC) remains unclear. We performed a multi-centre randomised phase III study comparing the use of Dexamethasone, Aspirin, and immediate addition of Diethylstilbestrol (DAiS) vs Dexamethasone, Aspirin, and deferred (until disease progression) addition of Diethylstilbestrol (DAdS).

机译：背景：进一步的激素治疗在去势抵抗性前列腺癌（CRPC）中的作用尚不清楚。我们进行了一项多中心随机III期研究，比较了地塞米松，阿司匹林和立即添加己烯雌酚（DAiS）与地塞米松，阿司匹林和延迟（直到疾病进展）地己烯雌酚（DAdS）添加的比较。

著录项

期刊名称 British Journal of Cancer
作者
J Shamash; T Powles; S J Sarker; A Protheroe; N Mithal; R Mills; R Beard; P Wilson; N Tranter; N OBrien; S McFaul; T Oliver;
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作者单位

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年(卷),期 2011(104),4
年度 2011
页码 620–628
总页数 9
原文格式 PDF
正文语种
中图分类肿瘤学;
关键词
CRPC Dexamethasone Diethylstilbestrol treatment sequencing;

机译：CRPC;地塞米松;己烯雌酚;治疗顺序;

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专利

1. A multi-centre randomised phase III trial of Dexamethasone vs Dexamethasone and diethylstilbestrol in castration-resistant prostate cancer: immediate vs deferred Diethylstilbestrol [J] . J Shamash, T Powles, S J Sarker, British Journal of Cancer . 2011,第4期

机译：一种多中心随机阶段III试验对阉割前列腺癌的地塞米松和二乙基胱糖醇：立即VS延迟二乙基斯特罗罗罗
2. A Randomised Phase 2 Trial of Dexamethasone Versus Prednisolone in Castration-resistant Prostate Cancer [J] . Venkitaraman Ramachandran, Lorente David, Murthy Vedang, European urology . 2015,第4期

机译：地塞米松与泼尼松龙在去势抵抗性前列腺癌中的随机2期试验
3. A randomised phase 2 trial of dexamethasone versus prednisolone in castration-resistant prostate cancer [J] . Ramachandran Venkitaraman, Vedang Murthy, Johann De Bono, Indian heart journal . 2015,第4期

机译：随机相2试验对抗阉割前列腺癌中的地塞米松与泼尼松龙
4. Castration-Resistant Prostate Cancer: Novel Targets, Agents, and Trials [C] . Evan Y. Yu Genitourinary Cancers Symposium . 2012

机译：抗阉割前列腺癌：新型靶点，药剂和试验
5. Sexuality and gynaecological cancer: A randomised control trial to evaluate the effectiveness of a group psychoeducational intervention in improving the sexual health of women with gynaecological cancer treated with radiotherapy [D] . Jeffries, Sherryl Anne 2003

机译：性与妇科癌症：一项随机对照试验，旨在评估团体心理教育干预措施对经放射治疗的妇科癌症妇女改善性健康的有效性
6. The MUK five protocol: a phase II randomised controlled parallel group multi-centre trial of carfilzomib cyclophosphamide and dexamethasone (CCD) vs. cyclophosphamide bortezomib (Velcade) and dexamethasone (CVD) for first relapse and primary refractory multiple myeloma [O] . Sarah Brown, Samantha Hinsley, Mónica Ballesteros, 2016

机译：MUK五种方案：卡非佐米环磷酰胺和地塞米松（CCD）与环磷酰胺硼替佐米（Velcade）和地塞米松（CVD）的II期随机对照平行组多中心试验用于首次复发和原发性难治性多发性骨髓瘤
7. A multi-centre randomised phase III trial of Dexamethasone vs Dexamethasone and diethylstilbestrol in castration-resistant prostate cancer: immediate vs deferred Diethylstilbestrol [O] . Shamash, J, Powles, T, Sarker, S J, 2011

机译：地塞米松，地塞米松和己烯雌酚治疗去势抵抗性前列腺癌的多中心随机III期试验：立即与递延己烯雌酚

A multi-centre randomised phase III trial of Dexamethasone vs Dexamethasone and diethylstilbestrol in castration-resistant prostate cancer: immediate vs deferred Diethylstilbestrol

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