Neopterin is associated with plaque inflammation and destabilisation in human coronary atherosclerotic lesions

摘要

BackgroundPrevious studies have shown that recent activation of the inflammatory response in coronary atherosclerotic lesions contributes to rapid progressive plaque destabilisation. Neopterin, a by‐product of the guanosine triphosphate pathway, is produced by activated macrophages and serves as an activation marker for monocytes/macrophages.