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Original research: Mesenchymal stromal/stem cells modulate response to experimental sepsis-induced lung injury via regulation of miR-27a-5p in recipient mice

机译：原始研究：间充质基质/干细胞通过调节miR-27a-5p调节小鼠对脓毒症诱发的肺损伤的反应

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摘要

Mesenchymal stromal cell (MSC) therapy mitigates lung injury and improves survival in murine models of sepsis. Precise mechanisms of therapeutic benefit remain poorly understood.

机译：间充质基质细胞（MSC）疗法减轻了脓毒症小鼠模型的肺部损伤并提高了其生存率。对治疗益处的精确机制仍知之甚少。

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期刊名称 BMJ Open Access
作者
Nadim Younes; Louis Zhou; Hajera Amatullah; Shirley H J Mei; Raquel Herrero; Jose Angel Lorente; Duncan J Stewart; Philip Marsden; W Conrad Liles; Pingzhao Hu; Claudia C dos Santos;
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年(卷),期 -1(75),7
年度 -1
页码 -1
总页数 12
原文格式 PDF
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关键词
ARDS; critical care; respiratory infection;

机译：ARDS;重症监护;呼吸道感染;

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专利

1. Mesenchymal stromal/stem cells modulate response to experimental sepsis-induced lung injury via regulation of miR-27a-5p in recipient mice [J] . Thorax: The Journal of the British Thoracic Society . 2020,第7期

机译：间充质基质/干细胞通过调节受体小鼠的miR-27a-5p调节对实验性脓毒症诱导的肺损伤的反应
2. Interleukin-10-Overexpressing Mesenchymal Stromal Cells Induce a Series of Regulatory Effects in the Inflammatory System and Promote the Survival of Endotoxin-Induced Acute Lung Injury in Mice Model [J] . Chenfei Wang, Dan Lv, Xiaobin Zhang, DNA and Cell Biology . 2018,第1期

机译：白细胞介素-10-过度抑制间充质基质细胞诱导炎症系统中的一系列调节作用，促进小鼠模型中内毒素诱导的急性肺损伤的存活
3. Endometrial Mesenchymal Stem/Stromal Cells Modulate the Macrophage Response to Implanted Polyamide/Gelatin Composite Mesh in Immunocompromised and Immunocompetent Mice [J] . S. Darzi, J. A. Deane, C. A. Nold, Scientific reports. . 2018,第1期

机译：子宫内膜间充质干细胞/基质细胞调节免疫受损和免疫功能小鼠对植入的聚酰胺/明胶复合网的巨噬细胞反应。
4. Mesenchymal Stem Cells Therapy for H9N2 Avian Influenza Viruses Induced Acute Lung Injury in Mice [C] . Li Yan, Chi Ying, Bian Qian, Biomedical Engineering and Biotechnology (iCBEB), 2012 International Conference on . 2012

机译：H9N2禽流感病毒间充质干细胞疗法引起的小鼠急性肺损伤
5. Mesenchymal stromal/stem cell-interpenetrating network biomatrices for modulating inflammatory host response in cutaneous healing and phagocyte-mediated impact on Staphylococcus aureus bioburden. [D] . Cantu, David Antonio. 2014

机译：间充质基质/干细胞互穿网络生物基质，用于调节皮肤愈合中的炎症宿主反应以及吞噬细胞介导的对金黄色葡萄球菌生物负荷的影响。
6. The Mechanisms Involved in Mesenchymal Stem Cell Alleviation of Sepsis-Induced Acute Lung Injury in Mice: A Pilot Study [O] . Feng Luo, Wei Jiang, Yan Xu, 2020

机译：参与败血症诱导的小鼠急性肺损伤的间充质干细胞的机制：试验研究
7. Mesenchymal stromal/stem cells modulate response to experimental sepsis-induced lung injury via regulation of miR-27a-5p in recipient mice [O] . Nadim Younes, Louis Zhou, Hajera Amatullah, 2020

机译：间充质基质/干细胞通过调节受体小鼠的miR-27a-5p调节对实验性脓毒症诱导的肺损伤的反应

Original research: Mesenchymal stromal/stem cells modulate response to experimental sepsis-induced lung injury via regulation of miR-27a-5p in recipient mice

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