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Efficacy and safety of a novel synergistic drug candidate CRx-102 in hand osteoarthritis

机译：新型协同药物CRx-102治疗手部骨关节炎的疗效和安全性

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摘要

Objective:The novel synergistic drug candidate CRx-102 comprises dipyridamole and low dose prednisolone and is in clinical development for the treatment of immunoinflammatory diseases. The purpose of this clinical study was to examine the efficacy and safety of CRx-102 in patients with hand osteoarthritis (HOA).

机译：目的：新型联用候选药物CRx-102包含双嘧达莫和小剂量泼尼松龙，正在临床上用于治疗免疫炎性疾病。这项临床研究的目的是检查CRx-102在手部骨关节炎（HOA）患者中的疗效和安全性。

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期刊名称 BMJ Open Access
作者
T K Kvien; E Fjeld; B Slatkowsky-Christensen; M Nichols; Y Zhang; A Prøven; K Mikkelsen; Ø Palm; A A Borisy; J Lessem;
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年(卷),期 -1(67),7
年度 -1
页码 942–948
总页数 7
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专利

1. Efficacy and safety of a novel synergistic drug candidate, CRx-102, in hand osteoarthritis. [J] . Kvien TK, Fjeld E, Slatkowsky-Christensen B, Annals of the Rheumatic Diseases: A Journal of Clinical Rheumatology and Connective Tissue Research . 2008,第7期

机译：新型协同药物CRx-102治疗手部骨关节炎的疗效和安全性。
2. Antithrombotic drug candidate ALX-0081 shows superior preclinical efficacy and safety compared with currently marketed antiplatelet drugs. [J] . Ulrichts H, Silence K, Schoolmeester A, Blood: The Journal of the American Society of Hematology . 2011,第3期

机译：与目前市售的抗血小板药物相比，抗血栓药物候选产品ALX-0081具有更好的临床前功效和安全性。
3. EFFICACY AND SAFETY OF INTRA-ARTICULAR CORTICOSTEROID ULTRASOUND-GUIDED INJECTION IN EROSIVE HAND OSTEOARTHRITIS [J] . Favero M., Hoxha A., Frallonardo P., Clinical and experimental rheumatology . 2018,第1Suppla109期

机译：关节内皮质类固醇超声引导注射症在腐蚀手骨关节炎中的疗效和安全性
4. Drug Piracy II: Quality, Efficacy and Safety Issues Related to Drug-Pirated Products ("compounded drug") and the Claims Associated with Them [C] . Joseph J. Bertone Annual Conference of American Association of Bovine Practitioners . 2004

机译：药物盗版二：与药物盗版产品（“复合药物”）和与他们相关的索赔有关的质量，疗效和安全问题
5. Part I: Hexosaminidase inhibitors as new drug candidates for the therapy of osteoarthritis. Part II: DERA-catalyzed asymmetric synthesis of novel pyranose synthons as a new entry to heterocycles and epothilones . [D] . Liu, Junjie. 2002

机译：第一部分：己糖胺酶抑制剂作为骨关节炎治疗的新药候选物。第二部分：DERA催化的新型吡喃糖合成子的不对称合成，作为杂环和埃博霉素的新入口。
6. Review: Efficacy and safety of non-pharmacological pharmacological and surgical treatment for hand osteoarthritis: a systematic literature review informing the 2018 update of the EULAR recommendations for the management of hand osteoarthritis [O] . Féline P B Kroon, Loreto Carmona, Jan W Schoones, 2018

机译：综述：非药物药理和外科治疗手性骨关节炎的疗效和安全性：系统文献综述通报了2018年更新的EULAR建议治疗手部骨关节炎
7. Efficacy and safety of a novel synergistic drug candidate, CRx-102, in hand osteoarthritis [O] . Kvien, T K, Fjeld, E, Slatkowsky-Christensen, B, 2007

机译：新型协同药物CRx-102治疗手部骨关节炎的疗效和安全性

Efficacy and safety of a novel synergistic drug candidate CRx-102 in hand osteoarthritis

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