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Case Report: Childhood hypopigmented mycosis fungoides: a commonly delayed diagnosis

机译:病例报告:儿童色素沉着性霉菌病:儿童通常的诊断延迟

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摘要

Primary cutaneous lymphomas (PCLs) are exceedingly rare in children and adolescents, with mycosis fungoides (MF) being the most frequent PCL diagnosed in childhood. There are numerous unusual clinical variants of MF, including the hypopigmented type form (HMF). HMF is exceptional overall, but comparatively common among children. We present an 8-year-old boy with a 3-year history of progressive, generalised, scaly, hypopigmented round patches and few erythematous papules. He was first diagnosed with pityriasis alba (PA), and moisturisers were prescribed with no improvement. Skin biopsy showed typical features of MF, and the patient was successfully treated with narrowband ultraviolet B. HMF may simulate atopic dermatitis, PA, pityriasis lichenoides, tinea versicolour, vitiligo, postinflammatory hypopigmentation or leprosy. Therefore, persistent and unusual hypopigmented lesions should be biopsied to rule out this rare variant of MF.
机译:原发性皮肤淋巴瘤(PCL)在儿童和青少年中极为罕见,其中真菌病菌(MF)是儿童时期最常见的PCL。 MF有许多不寻常的临床变异,包括色素不足型(HMF)。 HMF在总体上是例外,但在儿童中相对普遍。我们介绍了一个8岁男孩,有3年的进行性,全身性,鳞状,色素沉着的圆形斑块和少量红斑丘疹的病史。他首先被诊断出患有白癜风(PA),并且开了保湿霜后没有任何改善。皮肤活检显示了MF的典型特征,并且该患者已成功用窄带紫外线B治疗。HMF可以模拟特应性皮炎,PA,糠疹糠疹,扁平癣,白癜风,炎症后色素减退或麻风病。因此,应该对持续且异常色素沉着的病变进行活检,以排除这种罕见的MF变异。

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