AMLVaran: a software approach to implement variant analysis of targeted NGS sequencing data in an oncological care setting

摘要

Next-Generation Sequencing (NGS) enables large-scale and very cost-effective sequencing of genetic samples for the detection of mutations. Already being used in research worldwide, sequencing data is now starting to enter also routine care settings [ ]. It can be a valuable instrument for a better understanding of the emergence and prognosis of a disease [ ]. Also, it can help to optimize the type of treatment for personalized medicine [ ].