Blood signatures for second stage human African trypanosomiasis: a transcriptomic approach

摘要

Study design schematic. The flow-chart shows how the sampling was carried out. Individuals in the first stage with parasites (red dots) in blood and the uninfected (normal) had peripheral blood in paxgene tubes. For individuals in the second stage (red dots in the head) CSF containing parasites was centrifuged and the cells were resuspended in trizol. RNA was extracted and sequenced on the illumina platform