In vitro antibacterial and antibiotic-potentiation activities of the methanol extracts from Beilschmiedia acuta Clausena anisata Newbouldia laevis and Polyscias fulva against multidrug-resistant Gram-negative bacteria

摘要

BackgroundThe present study was designed to investigate the antibacterial activities of the methanol extracts from different parts of Beilschmedia acuta Kosterm (Lauraceae), Clausena anisata (Willd) Hook (Rutaceae), Newbouldia laevis Seem (Bignoniaceae) and Polyscias fulva (Hiern) Harms (Araliaceae) as well as their synergistic effects with antibiotics against a panel of Gram-negative bacteria, including multi-drug resistant (MDR) phenotypes expressing active efflux pumps.