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Thoracic Endovascular Aortic Repair for Acute Aortic Dissection

机译:胸腔内血管主动脉修复术治疗急性主动脉夹层

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摘要

Thoracic endovascular aortic repair (TEVAR) for thoracic aortic disease constitutes a paradigm shift in the treatment strategy of aortic dissection, as well as thoracic aortic aneurysms. Conventionally, most patients with Stanford type B acute aortic dissection are treated using conservative medical treatment during the acute phase. However, in patients with complicated type B aortic dissection who present with life-threatening complications, TEVAR has been introduced as a novel and less-invasive alternative and has shown better early results than those observed with conventional therapy. Recently, TEVAR was reported to be effective in not only promoting thrombosis of the false lumen but also in preventing aortic enlargement observed at long-term follow-up. TEVAR has been established as first-line therapy for complicated type B aortic dissection. In contrast, a considerable number of patients who received acute phase medical treatment required surgical intervention for chronic dissecting aortic aneurysms. With the increasing popularity of TEVAR for the treatment of complicated type B aortic dissection, prophylactic and pre-emptive TEVAR has been considered in patients with uncomplicated type B aortic dissection. However, supportive evidence for this strategy is limited, and reassessment is mandatory because it is continuously evolving. Although acute type A aortic dissection is a life-threatening condition, the results of open surgery continue to improve in the modern surgical era. Open surgical treatment is well established and recognized as a gold standard even in the endovascular era. Presently, the application of TEVAR for ascending aortic dissection has undergone a change, and TEVAR is considered a viable rescue option for patients with type A aortic dissection who are not eligible for open surgical repair. However, TEVAR for the descending aorta is well-established treatment for retrograde type A dissection. Several conceptual and technical issues remain unresolved, and technological advances would lead to the development of innovative disease-specific devices and solutions in the future for endovascular treatment of acute aortic dissection. (This is a translation of Jpn J Vasc Surg 2018; 27: 337–345.)
机译:胸主动脉疾病的胸腔内血管主动脉修复术(TEVAR)构成了主动脉夹层以及胸主动脉瘤的治疗策略的范式转变。常规上,大多数患有Stanford B型急性主动脉夹层的患者在急性期使用保守的药物治疗。然而,对于存在威胁生命的并发症的复杂B型主动脉夹层患者,TEVAR已被引入作为一种新的且创伤小的替代方案,并且比传统疗法具有更好的早期结果。最近,据报道TEVAR不仅可有效促进假管腔的血栓形成,而且可预防长期随访中观察到的主动脉肿大。 TEVAR已被确立为复杂的B型主动脉夹层的一线治疗方法。相比之下,接受急性期药物治疗的相当多的患者需要手术切除慢性夹层主动脉瘤。随着TEVAR在治疗复杂的B型主动脉夹层中的日益普及,已经对未复杂的B型主动脉夹层的患者进行了预防性和先发性TEVAR治疗。但是,该策略的支持证据有限,并且由于其不断发展,因此必须进行重新评估。尽管急性A型主动脉夹层是危及生命的疾病,但在现代手术时代,开放手术的结果仍在不断改善。开放式外科手术治疗是公认的,甚至在血管内时代也被认为是金标准。目前,TEVAR在升主动脉夹层中的应用发生了变化,TEVAR被认为是不适合进行开放式手术修复的A型主动脉夹层患者的可行挽救选择。但是,降主动脉的TEVAR是逆行A型夹层的行之有效的治疗方法。几个概念和技术问题仍未解决,技术进步将导致未来针对急性主动脉夹层血管内治疗的疾病特定器械和解决方案的开发。 (这是Jpn J Vasc Surg 2018的翻译; 27:337-345。)

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