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Sequence of 305996 total hip and knee arthroplasties in patients undergoing operations on more than 1 joint

机译:对超过1个关节进行手术的患者进行305996次全髋和膝关节置换术的顺序

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摘要

Background and purpose — Patient-specific data on multiple total arthroplasties (TA) of the lower limbs due to osteoarthritis (OA) are limited. We investigated the sequence of surgical procedures and risk factors for additional surgery in such patients.Patients and methods — 305,996 patients operated with a TA of the hip and/or knee due to OA were extracted from the Swedish National Hip (SHAR) and the Swedish Knee Arthroplasty Register (SKAR). 177,834 total hip arthroplasty (THA, 56% women, mean age 69 years) and 128,162 total knee arthroplasty (TKA, 60% women, mean age 69 years) procedures constituted the index operations. The mean, median, and maximum follow-up was 8, 6, and 23 years. Multivariable Cox regression analysis was used and Kaplan–Meier survival curves were constructed.Results — Right-sided primary TA (34%) was most frequent. Subsequent surgery was most frequent after primary left-sided TKA (33%). The time interval to a second TA procedure was 3.1 (SD 3.2) years after TKA and 4.0 (SD 3.9) years after THA. After the index TA the probability of no subsequent surgery amounted to 64% (SD 0.3) for THA and 58% (SD 0.4) for TKA over 20 years. Lower age, female sex, left side, and TKA at index operation were associated with a higher probability for subsequent TA.Interpretation — Delineation of factors that influence risk and the size of the risk for subsequent TA in 1 of the 3 major remaining joints is of value for clinicians and healthcare providers in the decision-making process for future resource allocation.
机译:背景与目的—由于骨关节炎(OA)而导致的下肢多种全关节置换术(TA)的患者特定数据有限。我们研究了此类患者的外科手术顺序和其他手术的危险因素。患者和方法-305,996例因OA而导致髋部和/或膝部TA手术的患者均来自瑞典国家髋关节(SHAR)和瑞典膝关节置换寄存器(SKAR)。 177例全髋关节置换术(THA,56%的女性,平均年龄69岁)和128,162例全膝关节置换术(TKA,60%的女性,平均年龄69岁)构成了指数手术。平均,中位数和最大随访时间为8、6和23年。使用多变量Cox回归分析并绘制了Kaplan–Meier生存曲线。结果—右侧原发性TA(34%)最常见。原发性左TKA后的后续手术最为频繁(33%)。再次进行TA手术的时间间隔为TKA后3.1(SD 3.2)年和THA后4.0(SD 3.9)年。在指标TA之后,在20年内,THA不再进行手术的可能性达到64%(SD 0.3),而TKA达到58%(SD 0.4)。较低的年龄,女性,左侧和进行分期手术时的TKA与随后发生TA的可能性较高有关。解释—在其余3个主要关节中的1个中,描述影响风险的因素和随后TA的风险大小为决策过程中对临床医生和医疗保健提供者的价值,以用于将来的资源分配。

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