神经元特异性烯醇化酶在儿童系统性红斑狼疮中的临床意义

摘要

Objective To investigate the clinical significance of neuron - specific enolase in children with systemic lupus erythematosus. Methods To detected serum NSE level of children ( 36 cases) with SLE by Electro - Chemiluminescence Immunoassay(ECLI). Results SLE group NSE level (18.8 ± 4. 5)ng/ml was significantly higher than control group (9. 1 ± 2. 5) ng/ml, (P <0. 05). Conclusion The NSE levels of children with SLE was significantly higher, The NSE may be used as a sensitive indicator early to judge whether there was lupus encephalopathy%目的 探讨神经元烯醇化酶(neuron specific enolase,NSE)在儿童系统性红斑狼疮(systemic lupus erythematosus,SLE)患者中的临床意义.方法 用电化学发光仪检测36例儿童SLE患者的血清NSE水平.结果 SLE组NSE水平(18.8±4.5)ng/ml,显著高于对照组的(9.1±2.5)ng/ml,差异有统计学意义(P<0.05).结论 SLE患者NSE水平明显升高,NSE有可能作为早期判断狼疮脑病是否存在的敏感指标.