超低频经颅磁刺激治疗非代偿性耳鸣的疗效分析

摘要

目的：观察超低频经颅磁刺激对非代偿性耳鸣的临床疗效。方法将52例非代偿性耳鸣患者随机分为观察组（27例）和对照组（25例），采用超低频经颅磁刺激分别对两组患者进行2周的真刺激和假刺激。治疗前后使用耳鸣障碍量表、焦虑自评量表、视觉模拟响度标尺（0-100）予以综合评估。结果治疗后第2、6、12周随访，观察组的耳鸣障碍量表、焦虑自评量表、视觉模拟响度标尺较治疗前及对照组相应时间点比较，差异均有统计学意义（P<0.05）。但对照组治疗前后各项评估比较，差异均无统计学意义（P>0.05）。治疗后第12周，观察组中17例患者耳鸣障碍量表评分降幅≥20分，有效率为62.96%；对照组仅2例患者降幅≥20分，有效率为8.00%，观察组疗效显著高于对照组，差异有统计学意义（P<0.05）。结论超低频经颅磁刺激可有效改善非代偿性耳鸣的继发症状，使患者适应耳鸣，提高生活质量。%ObjectiveObserve the therapeutic effect of ultra-low frequency transcranial magnetic stimulation on non-compensatory tinnitus. Methods 52 cases of Non-compensatory tinnitus patients were randomly divided into the treatment group(n=27) and the control group(n=25). Two groups were treated with active stimulus and sham stimulus treatment for 2 weeks respectively. The therapeutic comprehensive effects were assessed by tinnitus handicap inventory,self-rating anxiety scale and visual analog loudness scale(0-100).ResultsThe scores of THI,SAS and VAS in treatment group had statistically significance at 2 weeks,6weeks and 12 weeks follow-up. As compared with control group at the corresponding time,statistically significance were also found(P>0.05). There was no statistically significance in the control group before and after treatment (P>0.05). 12 weeks after the treatment,17 patients in treatment group had a decrease of THI rating by 20 points or more. While the control group had only 2 patients. So the effective rate was 63.0% and 8.0% respectively. The comparison between groups was statistically significant(P<0.05). Conclusions Ultra-low Frequency Transcranial Magnetic Stimulation can effectively improve the secondary symptoms of Non-compensatory tinnitus, to help the patients adapt the tinnitus and improve their quality of life.