cqvip:A 34-year-old woman presented with 2-year history of a domeshaped papule on a well-circumscribed, thickened, port-wine stain on the left side of the chin. Squeezing on the port-winestain plaque revealed many comedos within dilated follicular orifices. The papule was excised and submitted for histological examination. Histopathological study showed a lobular neoplasm, comprising dilated, cystic pilosebaceous structures surrounded by fibrous stroma, bearing the characteristics of folliculosebaceous cystic hamartoma. The reported case shows that, in addition to the vascular nature,both ectodermal and mesenchymal abnormalities may be involved in port-wine stains.
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