Objective: To examine the impact of financial compensation on pediatric asthm a research participation decision- making and determine whether perceptions of fair compensation differed for parents and adolescents, lower and higher income participants, and compensation- informedand uninformed participants in minimal and above minimal risk researc h. Study design: Adolescents (n = 36) with asthma and their parents reviewed 7 p ediatric asthma research protocols, decided whether they would choose to partici pate, and provided estimates of “ fair" compensation for their participation. C hi- square, analysis of variance, and analysis of covariance were used to deter mine the affects of compensation on participation and whether various respondent s differed in the perceptions of fair compensation. Results: Financial compensat ion did not affect participation decisions. Estimates of fair compensation were lower for adolescents, lower income respondents, and participants who were na ve about potential compensation. Fair compensation estimates were higher than ac tual compensation for minimal risk studies and lower for above minimal risk stud ies. Conclusions: Financial compensation may be a minor consideration in pediatr ic research participation decision- making. Still, differences in how pediatric researchers and their prospective participants judge fair compensation create t he potential for undue influence. Pediatric researchers should use caution when determining a reasonable financial compensation for research participation.
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