cqvip:We prospectively studied long- term (5 years) effects of endoscopic papillar y balloon dilation (EPBD) on gallbladder motility. Thirteen patients with intact gallbladders (six with and seven without gallbladder stones) who had undergone EPBD for choledocholithiasis were enrolled in this study. Gallbladder volumes, w hile fasting and after dried egg yolk ingestion, were determined by ultrasonogra phy, before and at 7 days, 1 month, and 1, 2, and 5 years after EPBD. Before EPB D, the gallbladder had a larger fasting volume and lower yolk- stimulated maxim um contraction than in normal controls. Seven days after EPBD, fasting volume wa s decreased and maximum contraction was increased, regardless of whether the pat ient had gallbladder stones, showing significant differences from the pre- EPBD values. At 1 month to 5 years after EPBD, these changes were far less evident a nd gallbladder function did not differ significantly from baseline. EPBD does no t adversely affect gallbladder motility in the long- term (5 years).
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