Giant xanthogranuloma of the pelvis with S1 origin:Complete removal with only posterior approach,technical note

摘要

Xanthogranulomas(XG)are benign proliferative disorder of histiocytes,a non-Langerhans cell histiocytosis.Whose etiology is unknown.The nature of these lesions is controversial and could be either reactive or neoplastic;the presence of monoclonal cells does,however,favor the second hypothesis.Xanthogranuloma is frequently found in young adults and children(under 20 years old),mainly in the skin.In about 5%-10%of all Juvenile XG(JXG)cases xanthogranuloma are extracutaneous.Within this group,the site most frequently involved is the eye.Other involved organs are heart,liver,adrenals,oropharynx,lung,spleen,central nervous system and subcutaneous tissue,although involvement of the spine is uncommon.Isolated lesions involving the sacral region are extremely rare.To date,this is the first reported case of a giant JXG arising from S1 with extension into the pelvic region in an adult spine.