经皮肺穿刺注药结合利肺片治疗耐多药空洞型肺结核疗效分析

摘要

目的:探讨CT引导经皮肺穿刺注药结合利肺片治疗耐多药空洞型肺结核的疗效.方法:将84例耐多药空洞型肺结核患者随机分为2组,介入治疗组采用经皮肺穿刺、空洞注入含抗结核药物凝胶配合全身化疗和利肺片治疗,对照组单用抗结核药物治疗.结果:介入治疗组痰菌阴转率73.3%、病灶吸收率71.1%、空洞闭合率47.4%,明显高于对照组,2组比较差异有统计学意义.结论:CT引导经皮肺穿刺注药配合全身化疗和利肺片治疗治疗耐多药空洞型肺结核,疗效优于单纯全身化疗,操作安全,不良反应少.%Objective:To explore the therapeutic effect of CT-guided percutaneous pneumocentesis perfusion combined with lifei tablet in treating cavernous multi-drug resistant pulmonary tuberculosis.Methods:Eighty four patients suffered from cavernous multi-drug resistant pulmonary tuberculosis were randomly divided into two groups.Patients in treatment group received gel perfusion containing antitubercu-lar drugs through CT-guided percutaneous pneumocentesis,as well as general chemotherapy and lifei tablet.Patients in control group were only given antitubercular drugs.Results:The sputum negative conversion rate was 73.3% ,foci absorption rate was 71.1% ,and cavity closure rate was 47.4% in the treatment group ,all of which were higher than those of the control group.There were significant differences between the two groups.Conclusion:CT-guided percutaneous pneumocentesis perfusion combined with chemotherapy and lifei tablet showed better therapeutic effect than chemotherapy in treating cavernous multi-drug resistant pulmonary tuberculosis with safe procedure and few side effects.