奇正消痛贴膏治疗急性腰扭伤和腰扭伤后陈旧性伤痛的药物经济学分析

摘要

目的：比较奇正消痛贴膏和扶他林乳胶剂两种治疗方案对急性腰扭伤和腰扭伤后陈旧性伤痛的药物经济学差异。方法：在北京、上海、广州和通辽收集急性腰扭伤病例299例，根据医生的实际处方给药，观察治疗前后的健康结果和生活质量（EQ -5D），并分析两种治疗方案的成本-效果和成本-效用。结果：与扶他林乳胶剂相比奇正消痛贴膏在14 d 能显著缩短疼痛时间（P ＜0.001），而且14 d、28 d 在疼痛、压痛、脊柱活动障碍方面效果均优于扶他林乳胶剂。结论：奇正消痛贴膏与扶他林乳胶剂相比具有成本-效果优势。%Objective:To compare the pharmaco-economic difference of Qizheng Xiaotong Plaster and Voltaren Emulsion on Acute and prolonged lumbar sprain.Methods:Total of 299 Acute lumbar sprain patients took Qizheng Xiaotong Plaster and Voltaren Emulsion and observed effectiveness and health-related quality of life (EQ-5D),and conducted cost-effectiveness analysis and cost-utility analysis. Results:Qizheng Xiaotong Plaster can significantly relieve the pain at day14 (P <0.001),and alleviated other symptoms of tenderness, movement disorder,spinalare better than Voltaren Emulsion at day14 and day28.Conclusion:The Qizheng Xiaotong Plaster was more cost-effective than Voltaren Emulsion.