大肠癌中医证候微观辨证的研究进展

摘要

Objective:To summarize and analyze the research progress on microcosmic syndrome differentiation of colorectal cancer. Methods:Electronic and manual retrieval were used to go through literatures from 2003 to 2013 in CNKI and Wan Fang DATA on mi-croscopic syndrome differentiation of colorectal cancer.Results:Literatures on microscopic syndromes differentiation of colorectal cancer focused on several aspects of pathological type and stage,serum markers,gene and protein expression,lesion,metastasis and cachexia situation,etc.Conclusion:Because there is no acknowledged standard on the TCM syndrome differentiation of colorectal cancer,and the corresponding methods are not yet mature,the studies of colorectal cancer microscopic syndromes differentiation need to further in-crease the sample size and improve research techniques.%目的：整理分析大肠癌中医证候微观辨证的研究进展。方法：结合机器检索与人工手检，检索2003-2013年CNKI及万方数据库关于大肠癌中医证候微观辨证的文献。结果：大肠癌中医证候微观辨证的相关文献主要从病理分型及分期、血清标志物、基因与蛋白表达、病变部位、转移情况和恶病质情况等几个方面探讨。结论：由于其中医辨证分型尚未有统一的标准，相应研究方法也尚未成熟，大肠癌的中医证候微观辨证还需要进一步增加样本量，完善研究技术，使大肠癌的微观辨证研究更加客观，为临床治疗提供借鉴。