邓成珊攻补兼施治疗原发性骨髓纤维化经验

摘要

原发性骨髓纤维化属中医“虚劳”“积聚”“髓枯”等病范畴，邓成珊教授认为本病系形神过耗，劳倦内伤所致，病性本虚而标实。其本虚主要责之于脾肾两脏，标实则以瘀血为基础，或久蕴化毒，或兼有湿热、水饮。治疗当攻补兼施，补益脾肾，活血化瘀，散结软坚。在辨证论治的基础上常用桃仁、赤芍、丹参、鳖甲等药物。%Primary myelofibrosis belonged to Chinese medicine of “consumptive disease”,“accumulation disease”and “bone marrow depletion”category.Professor Deng Chengshan believed that the cause of primary myelofibrosis was the excessive con-sumption of ones body and spirit,so that overstrain led to disorders of internal organs.The essence of the disease was deficiency in origin and excess in superficiality.The main responsibility of deficiency was due to the asthenia of spleen and kidney.And blood stasis was the foundation of evil repletion.Stagnant blood changed into toxic pathogens after long-term accumulation,or was accompanied with dampness-heat or retained fluid.Tonification and purgation in combination was the method to treat,including promoting blood circulation for removing blood stasis,resolving hard lump and invigorating spleen and kidney.On the basis of treatment according to syndrome differentiation,peach kernel,radix paeoniae rubra,radix salviae miltiorrhizae,turtle shell and other herbs were used frequently.