PRIMARY MYELOFIBROSIS CELL MODEL AND USES THEREOF

摘要

The present invention relates to primary myelofibrosis cell models and uses thereof. The megakaryocyte-erythrocyte progenitor cell of the present invention exhibits characteristics such as excessive proliferation of progenitor cells and reduced differentiation into megakaryocytes or platelets, similar to primary myelofibrosis, and can be used to screen a therapeutic drug for primary myelofibrosis. . Therefore, the megakaryocyte-erythrocyte progenitor cells of the present invention can be usefully used in the development of a therapeutic agent for primary myelofibrosis.