中药治疗亚急性甲状腺炎疗效Me ta分析

摘要

Objective:To evaluate the efficacy and safety of Traditional Chinese medicine treatment of hyperthyroidism.Methods:computer retrieval literature about clinical research of traditional Chinese medicine in the treatment of hyperthyroidism,selected RCT&CCT researches in human body comply with the requirements from the establishment to 201 4 since January,Meta analysis was performed to assess the quality of literatures,by using RevMan 5 .2 software(download from Corhrane collaboration network), using Cochrane manual to evaluate the articles.Results:in the 1 6 randomized controlled trials involving 702 patients were includ-ed,661 patients were effective,controlled group involving 590 patients were included,462 patients were effective.Meta analysis showed that the traditional Chinese medicine in the treatment of subacute thyroiditis and simple western medicine in the treatment of total effective rate(cure &better),the difference was statistically significant[OR=0.22,95%CI(0.1 5,0.33),Z=7.76,P<0.01 ].Conclusion:the effective rate and cure rate is better than pure western medicine group using traditional Chinese medicine treatment of subacute thyroiditis.%目的：评价中药治疗甲状腺功能亢进症的有效性及安全性。方法：计算机检索关于中药治疗甲亢的人体临床试验研究文献，选择从1980年1月至2014年1月符合要求的随机对照试验（RCT）和临床对照试验（CCT）的文章，并按排除原则进行筛选，利用Cochrane手册进行文献质量评价，利用RevMan 5.2软件进行Meta分析。结果：共纳入16篇随机对照试验，所有文献入组患者合计702例，有效661例，对照组合计590例，有效462例。Meta分析结果显示，中药治疗亚急性甲状腺炎与单纯西药治疗比较总有效率（治愈率＋好转率）的差异有统计学意义[OR＝0.22，95％CI（0.15，0.33），P＜0.01]。结论：采用中药治疗亚急性甲状腺炎的总有效率和治愈率明显优于单纯使用西药。