电鍉针循经感传治疗偏头痛的疗效观察及机制探析

摘要

Objective:To observe the curative effect and part of the mechanism discussion of electric arrowhead needle propagated sensation along channel in the treatment of migraine. Methods:Eighty cases of patients with migraine in our hospital during January 2014-January 2015 were included in the study,randomly divided into the conventional group and the observation group,40 cases in each group. The conventional group used electric arrowhead needle with non-acupoint,the observation group used electric arrowhead needle propagated sensation along channel,1 time/day,30 min/time,5 times a week,both of the two groups had continuous treat-ment for 4 weeks,at the time of the 2nd week,the 4th week after the treatment,compared the two groups of patients with migraine attack frequency,headache days,McGill scores,Anxiety and depression self rating scale score,contemporary compared BDNF con-centration changes before and after treatment of the two groups. Results:1)2 weeks after the treatment,both of the two groups of pa-tients with migraine,McGill scores were with obvious reduction,the headache days were shortened,the various indicators of the two groups were with no statistical differences(P>0. 05);2)4 weeks after treatment,the indicators in both the two groups continue im-proved,the improved trend of the observation group were significantly than the control group(P<0. 05). 3)Peripheral blood con-centrations of BDNF in the patients of the two groups were significantly decreased after treatment,the downward trend in the obser-vation group was more obvious(P<0. 05). Conclusion:Electric arrowhead needle propagated sensation along channel can obvious-ly improve the symptoms of migraine,and with obvious persisitency effect,this may be related to the reduction of BDNF in the pa-tients.%目的：：观察电鍉针循经感传对偏头痛的临床疗效及部分机制探讨。方法：将本院2014年1月至2015年1月80例偏头痛患者纳入研究,随机分为常规组和观察组,各40例。常规组采用电鍉针非经非穴,观察组采用电鍉针循经感传手法,治疗1次/d,约30 min/次,5次/周,2组均连续治疗四周,治疗第2周、第4周时比较2组患者偏头痛发作次数、头痛天数、McGill疼痛评分、焦虑和抑郁自评量表评分,同时比较2组治疗前后BDNF浓度变化。结果：1)治疗2周后2组患者偏头痛发作次数、McGill疼痛评分、明显减少、头痛天数较治疗前缩短,此时2组各指标差异无统计学意义( P>0．05)；2)治疗4周后2组患者上述治疗继续改善,此时观察组改善的趋势较对照组明显(P<0．05)；3)治疗后2组患者外周血BDNF浓度均较治疗前明显下降,其中观察组下降的趋势更明显(P<0．05)。结论：电鍉针循经感传可明显改善偏头痛症状,且具有明显持续效应,这可能与其可降低患者BDNF有关。